Protein S-nitrosylation: purview and parameters

DT Hess, A Matsumoto, SO Kim, HE Marshall… - … reviews Molecular cell …, 2005 - nature.com
S-nitrosylation, the covalent attachment of a nitrogen monoxide group to the thiol side chain
of cysteine, has emerged as an important mechanism for dynamic, post-translational …

Nitric oxide production and signaling in inflammation

R Korhonen, A Lahti, H Kankaanranta… - Current Drug Targets …, 2005 - ingentaconnect.com
Nitric oxide (NO) is recognized as a mediator and regulator of inflammatory responses. It
possesses cytotoxic properties that are aimed against pathogenic microbes, but it can also …

Redox regulation of protein kinases

A Corcoran, TG Cotter - The FEBS journal, 2013 - Wiley Online Library
Reactive oxygen species (ROS) have been long regarded as by‐products of a cascade of
reactions stemming from cellular oxygen metabolism, which, if they accumulate to toxic …

Toward understanding the selective anticancer capacity of cold atmospheric plasma—A model based on aquaporins

D Yan, A Talbot, N Nourmohammadi, JH Sherman… - …, 2015 - pubs.aip.org
Selectively treating tumor cells is the ongoing challenge of modern cancer therapy.
Recently, cold atmospheric plasma (CAP), a near room-temperature ionized gas, has been …

Evidence of oxidative stress in human corneal diseases

R Buddi, B Lin, SR Atilano… - … of Histochemistry & …, 2002 - journals.sagepub.com
This study localized malondialdehyde (MDA, a toxic byproduct of lipid peroxidation),
nitrotyrosine [NT, a cytotoxic byproduct of nitric oxide (NO)], and nitric oxide synthase …

Brain micro-ecologies: neural stem cell niches in the adult mammalian brain

PA Riquelme, E Drapeau… - … Transactions of the …, 2008 - royalsocietypublishing.org
Neurogenesis persists in two germinal regions in the adult mammalian brain, the
subventricular zone of the lateral ventricles and the subgranular zone in the hippocampal …

A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity

M Compte, SL Harwood, IG Muñoz, R Navarro… - Nature …, 2018 - nature.com
The costimulation of immune cells using first-generation anti-4-1BB monoclonal antibodies
(mAbs) has demonstrated anti-tumor activity in human trials. Further clinical development …

Redox regulation of epidermal growth factor receptor signaling through cysteine oxidation

TH Truong, KS Carroll - Biochemistry, 2012 - ACS Publications
Epidermal growth factor receptor (EGFR) exemplifies the family of receptor tyrosine kinases
that mediate numerous cellular processes, including growth, proliferation, and …

Nitric oxide is a physiological inhibitor of neurogenesis in the adult mouse subventricular zone and olfactory bulb

B Moreno-López, C Romero-Grimaldi… - Journal of …, 2004 - Soc Neuroscience
The subventricular zone of the rodent brain retains the capacity of generating new neurons
in adulthood. The newly formed neuroblasts migrate rostrally toward the olfactory bulb …

Airway structural components drive airway smooth muscle remodeling in asthma

BGJ Dekkers, H Maarsingh, H Meurs… - Proceedings of the …, 2009 - atsjournals.org
Chronic asthma is an inflammatory airways disease characterized by pathological changes
in the airway smooth muscle (ASM) bundle that contribute to airway obstruction and …