Recent progress in polymeric non-invasive insulin delivery

F Sabbagh, II Muhamad, R Niazmand… - International journal of …, 2022 - Elsevier
The design of carriers for insulin delivery has recently attracted major research attentions in
the biomedical field. In general, the release of drug from polymers is driven via a variety of …

Alternatives to eye bank native tissue for corneal stromal replacement

I Brunette, CJ Roberts, F Vidal… - Progress in retinal and …, 2017 - Elsevier
Corneal blindness is a major cause of blindness in the world and corneal transplantation is
the only widely accepted treatment to restore sight in these eyes. However, it is becoming …

A selective, hydrogel‐based prodrug delivery system efficiently activates a suicide gene to remove undifferentiated human stem cells within neural grafts

KCL Law, N Mahmoudi, ZE Zadeh… - Advanced Functional …, 2023 - Wiley Online Library
The directed differentiation of human pluripotent stem cells (hPSCs) into defined populations
has advanced regenerative medicine, especially for Parkinson's disease where clinical trials …

Acrylamide-based hydrogel drug delivery systems: release of acyclovir from MgO nanocomposite hydrogel

F Sabbagh, II Muhamad - Journal of the Taiwan Institute of Chemical …, 2017 - Elsevier
Polyacrylamide-based hydrogels were obtained by chemical crosslinking of MBA using
acrylamide, sodium carboxymethylecellulose (NaCMC), N, N, N', N' …

Folic acid-modified celastrol nanoparticles: synthesis, characterization, anticancer activity in 2D and 3D breast cancer models

S Law, AW Leung, C Xu - Artificial Cells, Nanomedicine, and …, 2020 - Taylor & Francis
Celastrol is used in traditional Chinese medicine for treating cancers. However, its low water
solubility and poor tumour selection represent major pitfalls for clinical application. In the …

[HTML][HTML] Cathelicidin LL-37 and HSV-1 corneal infection: peptide versus gene therapy

CJ Lee, O Buznyk, L Kuffova, V Rajendran… - … vision science & …, 2014 - arvojournals.org
Purpose:: To evaluate the potential utility of collagen-based corneal implants with anti–
Herpes Simplex Virus (HSV)-1 activity achieved through sustained release of LL-37, from …

[HTML][HTML] High-risk corneal allografts: a therapeutic challenge

T Yu, V Rajendran, M Griffith, JV Forrester… - World journal of …, 2016 - ncbi.nlm.nih.gov
Corneal transplantation is the most common surgical procedure amongst solid organ
transplants with a high survival rate of 86% at 1-year post-grafting. This high success rate …

Heterogeneous polymer composite nanoparticles loaded in situ gel for controlled release intra-vaginal therapy of genital herpes

D Ramyadevi, KS Rajan, BN Vedhahari… - Colloids and Surfaces B …, 2016 - Elsevier
Herpes simplex virus causes serious and contagious genital infections in high percentage of
female population world-wide. Acyclovir is a clinically successful antiviral molecule till date …

Regenerative approaches as alternatives to donor allografting for restoration of corneal function

M Griffith, N Polisetti, L Kuffova, J Gallar, J Forrester… - The ocular …, 2012 - Elsevier
A range of alternatives to human donor tissue for corneal transplantation are being
developed to address the shortfall of good quality tissues as well as the clinical conditions …

Structure–activity relationships of GAG mimetic-functionalized mesoporous silica nanoparticles and evaluation of acyclovir-loaded antiviral nanoparticles with dual …

EC Lee, CTH Nguyen, E Strounina, N Davis-Poynter… - ACS …, 2018 - ACS Publications
Mesoporous silica nanoparticles (MSNs) are drug delivery agents that are able to
incorporate drugs within their pores. Furthermore, MSNs can be functionalized by …