In Vitro Analyses of the Toxicity, Immunological, and Gene Expression Effects of Cobalt-Chromium Alloy Wear Debris and Co Ions Derived from Metal-on-Metal Hip …

OM Posada, RJ Tate, RMD Meek, MH Grant - Lubricants, 2015 - mdpi.com
Joint replacement has proven to be an extremely successful and cost-effective means of
relieving arthritic pain and improving quality of life for recipients. Wear debris-induced …

CoCr wear particles generated from CoCr alloy metal-on-metal hip replacements, and cobalt ions stimulate apoptosis and expression of general toxicology-related …

OM Posada, D Gilmour, RJ Tate, MH Grant - Toxicology and applied …, 2014 - Elsevier
Cobalt-chromium (CoCr) particles in the nanometre size range and their concomitant
release of Co and Cr ions into the patients' circulation are produced by wear at the …

Effect of cyclosporin A on the viability of hippocampal cells cultured under conditions of modeling of Alzheimer's disease

EV Kravenska, VV Ganzha, EN Yavorskaya… - Neurophysiology, 2016 - Springer
The presence of amyloid plaques and neurofibrillary tangles accompanied by
manifestations of intense neurodegeneration in the brain is the main syndrome of …

Study of the toxicity, immunological and gene expression effects of cobalt ions and wear debris derived from metal-on-metal hip implants

OM Posada Estefan - 2013 - stax.strath.ac.uk
Joint replacements have been used for over 30 years with considerable success as
treatment for bone diseases. As a surgical alternative to metal on metal (MoM) total hip …

Cobalt induced cardiotoxicity: a suspected adverse effect associated with COCR alloy orthopaedic implants

S Laovitthayanggoon - 2018 - stax.strath.ac.uk
Cobalt toxicity, arising from the release of metal nanoparticles and ions during wear of Co/Cr
metal-on-metal (MoM) hip implants has become a recognised internal source of Co …

Вплив циклоспорину А на життєздатність культивованих клітин гіпокампа при моделюванні хвороби Альцгеймера

ЄВ Кравенська, ВВ Ганжа, ОМ Яворська… - …, 2016 - dspace.nbuv.gov.ua
Присутність амілоїдних бляшок і нейрофібрилярних клубків та прояви інтенсивної
нейродегенерації в мозку є основними патологічними явищами, характерними для …