The silent epidemic of chronic pain in older adults

AF Domenichiello, CE Ramsden - Progress in Neuro-Psychopharmacology …, 2019 - Elsevier
Chronic pain is highly prevalent among older adults where it is associated with significant
suffering, disability, social isolation, and greater costs and burden to health care systems …

Chronic pain in the elderly: mechanisms and perspectives

APA Dagnino, MM Campos - Frontiers in Human Neuroscience, 2022 - frontiersin.org
Chronic pain affects a large part of the population causing functional disability, being often
associated with coexisting psychological disorders, such as depression and anxiety …

Changes in cognitive function and risk factors for cognitive impairment of the elderly in China: 2005–2014

Q Zhang, Y Wu, T Han, E Liu - International journal of environmental …, 2019 - mdpi.com
Background: The cognitive function of the elderly has become a focus of public health
research. Little is known about the changes of cognitive function and the risk factors for …

Elevated dementia risk, cognitive decline, and hippocampal atrophy in multisite chronic pain

W Zhao, L Zhao, X Chang, X Lu… - Proceedings of the …, 2023 - National Acad Sciences
Numerous studies have investigated the impacts of common types of chronic pain (CP) on
patients' cognitive function and observed that CP was associated with later dementia. More …

Consideration of sex and gender in Alzheimer's disease and related disorders from a global perspective

MM Mielke, NT Aggarwal, C Vila‐Castelar… - Alzheimer's & …, 2022 - Wiley Online Library
Sex or gender differences in the risk of Alzheimer's disease and related dementias (ADRD)
differ by world region, suggesting that there are potentially modifiable risk factors for …

Health in citizen‐state interactions: How physical and mental health problems shape experiences of administrative burden and reduce take‐up

E Bell, J Christensen, P Herd… - Public Administration …, 2023 - Wiley Online Library
Public services represent a key means by which societies seek to reduce inequalities.
However, some people may experience administrative procedures as more burdensome …

The link between chronic pain and Alzheimer's disease

S Cao, DW Fisher, T Yu, H Dong - Journal of neuroinflammation, 2019 - Springer
Chronic pain often occurs in the elderly, particularly in the patients with neurodegenerative
disorders such as Alzheimer's disease (AD). Although studies indicate that chronic pain …

Chronic musculoskeletal pain and its impact on older people

FM Blyth, N Noguchi - Best practice & research Clinical rheumatology, 2017 - Elsevier
Musculoskeletal conditions are the leading cause of disability worldwide and also have a
large impact on many other aspects of older people's health such as low physical activity …

A biopsychosocial model of chronic pain for older adults

C Miaskowski, F Blyth, F Nicosia, M Haan… - Pain …, 2020 - academic.oup.com
Population Comprehensive evaluation of chronic pain in older adults is multifaceted.
Objective and Methods Research on chronic pain in older adults needs to be guided by …

Cathepsin B in neurodegeneration of Alzheimer's disease, traumatic brain injury, and related brain disorders

V Hook, M Yoon, C Mosier, G Ito, S Podvin… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Investigations of Alzheimer's disease (AD), traumatic brain injury (TBI), and related brain
disorders have provided extensive evidence for involvement of cathepsin B, a lysosomal …