The cochlea of the mammalian inner ear includes an active, hydromechanical amplifier
thought to arise via the piezoelectric action of the outer hair cells (OHCs). A classic problem …

The voltage-dependent protein SLC26a5 (prestin) underlies outer hair cell electromotility
(eM), which is responsible for cochlear amplification in mammals. The electrical signature of …

Charged moieties in the outer hair cell (OHC) membrane motor protein, prestin, are driven
by transmembrane voltage to power OHC electromotility (eM) and cochlear amplification …

The outer hair cell (OHC) of the organ of Corti underlies a process that enhances hearing,
termed cochlear amplification. The cell possesses a unique voltage-sensing protein, prestin …

Several studies have documented the early development of OHC electromechanical
behavior. The mechanical response (electromotility, eM) and its electrical correlate …

Outer hair cell (OHC) nonlinear capacitance (NLC) represents voltage sensor charge
movements of prestin (SLC26a5), the protein responsible for OHC electromotility. Previous …

The outer hair cell (OHC) membrane harbors a voltage-dependent protein, prestin
(SLC26a5), in high density, whose charge movement is evidenced as a nonlinear …

Outer hair cell (OHC) nonlinear membrane capacitance derives from voltage-dependent
sensor charge movements within the membrane protein prestin (SLC26a5) that drive OHC …

In general, SLC26 solute carriers serve to transport a variety of anions across biological
membranes. However, prestin (SLC26a5) has evolved, now serving as a motor protein in …

Hearing is an extremely delicate sense that is particularly vulnerable to insults from
environment, including drugs and noise. Unsurprisingly, mice of different genetic …