Oral drug administration is one of the most preferred and simplest routes among both
patients and formulation scientists. Nevertheless, orally delivery of some of the most widely …

The limited number of oral vaccines currently approved for use in humans and veterinary
species clearly illustrates that development of efficacious and safe oral vaccines has been a …

Lactic acid bacteria (LAB) are promising vectors of choice to deliver active molecules to
mucosal tissues. They are recognized as safe by the World Health Organization and some …

The probiotic yeast Saccharomyces cerevisiae var boulardii is widely used as a low cost and
efficient adjuvant against gastrointestinal tract disorders such as inflammatory bowel …

Infectious diseases continue to inflict a high global disease burden. The consensus is that
vaccination is the most effective option against infectious diseases. Oral vaccines have …

Over the past 20 years, a variety of potential adjuvants have been studied to enhance the
effect of oral vaccines in the intestinal mucosal immune system; however, no licensed …

Background Chicken coccidiosis is a protozoan disease that leads to considerable
economic losses in the poultry industry. Live oocyst vaccination is currently the most …

Background Dendritic cell (DC) targeted antigen delivery is a promising strategy to enhance
vaccine efficacy and delivery of therapeutics. Self-assembling peptide-based nanoparticles …

Background Porcine epidemic diarrhea caused by porcine epidemic diarrhea virus (PEDV)
has led to serious economic losses to the swine industry worldwide. In this study, an oral …

The mucosal immune system is a compartmentalized part of the immune system that
provides local immunity in the mucosa of the respiratory, gastrointestinal, and digestive …