Hepatocellular carcinoma (HCC) is an aggressive disease with a poor clinical outcome. The
cancer stem cell (CSC) model states that tumour growth is powered by a subset of tumour …

Hepatocellular carcinoma (HCC) is one of the leading cancers worldwide. Classically, HCC
develops in genetically susceptible individuals who are exposed to risk factors, especially in …

Importance Cirrhosis affects approximately 2.2 million adults in the US. From 2010 to 2021,
the annual age-adjusted mortality of cirrhosis increased from 14.9 per 100 000 to 21.9 per …

The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which
not only arise during metabolic functions but also during the biotransformation of …

More than 90% of cases of hepatocellular carcinoma (HCC) occurs in patients with cirrhosis,
of which hepatitis B virus and hepatitis C virus are the leading causes, while the tumor less …

Autoimmune hepatitis is an inflammatory disease of the liver of unknown cause that may
progress to liver cirrhosis and end stage liver failure if diagnosis is overlooked and treatment …

Liver cancer is considered one of the deadliest diseases with one of the highest disease
burdens worldwide. Among the different types of liver cancer, hepatocellular carcinoma is …

Chronic liver disease and primary liver cancer are a massive global problem, with a future
increase in incidences predicted. The most prevalent form of primary liver cancer …

Introduction: Hepatocellular carcinoma (HCC) is the sixth most commonly diagnosed cancer
and the third leading cause of cancer death worldwide. While there has been rapid evolution …

Haemochromatosis is characterised by elevated transferrin saturation (TSAT) and
progressive iron loading that mainly affects the liver. Early diagnosis and treatment by …