Confined acids catalyze asymmetric single aldolizations of acetaldehyde enolates

L Schreyer, PSJ Kaib, VN Wakchaure, C Obradors… - Science, 2018 - science.org
Reactions that form a product with the same reactive functionality as that of one of the
starting compounds frequently end in oligomerization. As a salient example, selective aldol …

Synthesis of 1, 3-diols by O-nucleophile additions to activated alkenes

D Gamba-Sánchez, J Prunet - Synthesis, 2018 - thieme-connect.com
The diastereoselective synthesis of 1, 3-diols by addition of oxygen nucleophiles to activated
alkenes is presented. This review focuses on homoallylic alcohol substrates that react with a …

The chemistry of the carbon-transition metal double and triple bond: Annual survey covering the year 2017

JW Herndon - Coordination Chemistry Reviews, 2018 - Elsevier
This is a review of papers published in the year 2017 that focus on the synthesis, reactivity,
or properties of compounds containing a carbon-transition metal double or triple bond …

Organocatalytic Enantio- and Diastereoselective Construction of syn-1,3-Diol Motifs via Dynamic Kinetic Resolution of In Situ Generated Chiral Cyanohydrins

A Matsumoto, K Asano, S Matsubara - Organic letters, 2019 - ACS Publications
An organocatalytic method for the asymmetric synthesis of syn-1, 3-dioxanes as protected 1,
3-diols via dynamic kinetic resolution of in situ generated chiral cyanohydrins has been …

Racemic hemiacetals as oxygen-centered pronucleophiles triggering cascade 1, 4-addition/Michael reaction through dynamic kinetic resolution under iminium …

A Orue, U Uria, D Roca-López, I Delso, E Reyes… - Chemical …, 2017 - pubs.rsc.org
2-Hydroxydihydropyran-5-ones behave as excellent polyfunctional reagents able to react
with enals through oxa-Michael/Michael process cascade under the combination of iminium …

Synthesis of Nitrile‐Bearing Quaternary Centers by an Equilibrium‐Driven Transnitrilation and Anion‐Relay Strategy

S Alazet, MS West, P Patel… - Angewandte Chemie …, 2019 - Wiley Online Library
The efficient preparation of nitrile‐containing building blocks is of interest due to their utility
as synthetic intermediates and their prevalence in pharmaceuticals. As a result, significant …

Tandem Three‐Component Synthesis of syn‐1,2‐ and syn‐1,3‐Diol Derivatives

K Murata, H Takeshita, K Sakamoto… - Chemistry–An Asian …, 2020 - Wiley Online Library
The development of efficient methods for stereocontrolled synthesis of polyol derivatives has
been of continuing interest for the synthetic community. We describe herein tandem olefin …

An intramolecular oxa-Michael reaction on α, β-unsaturated α-amino-δ-hydroxycarboxylic acid esters. Synthesis of functionalized 1, 3-dioxanes

L Becerra-Figueroa, S Movilla, J Prunet… - Organic & …, 2018 - pubs.rsc.org
A highly diastereoselective intramolecular oxa-Michael reaction on α, β-unsaturated α-
amino-δ-hydroxycarboxylic acid esters is presented; 1, 3-dioxanes functionalized in …

Conceptual design and cost-efficient environmentally Benign synthesis of beta-lactams

A Das, RN Yadav, BK Banik - Physical Sciences Reviews, 2023 - degruyter.com
Stereoselective preparation of diverse trans and cis β-lactams following different
experimental conditions are executed. A variety of circumstances are critically analyzed. It …

[图书][B] Synthesis of Bioactive Scaffolds

RK Sharma, B Banerjee - 2022 - books.google.com
Carbon-carbon and carbon-heteroatom bond-forming reactions are the backbone of
synthetic organic chemistry. Scientists are constantly developing and improving these …