A review of romiplostim mechanism of action and clinical applicability

JB Bussel, G Soff, A Balduzzi, N Cooper… - Drug design …, 2021 - Taylor & Francis
Thrombocytopenia results from a variety of conditions, including radiation, chemotherapy,
autoimmune disease, bone marrow disorders, pathologic conditions associated with …

Clinical challenges and promising therapies for chemotherapy-induced thrombocytopenia

H Al‐Samkari, GA Soff - Expert review of hematology, 2021 - Taylor & Francis
Introduction: Chemotherapy-induced thrombocytop enia (CIT) is a common complication of
cancer treatment causing chemotherapy delays, dose reductions, and treatment …

Systematic literature review and meta-analysis on use of Thrombopoietic agents for chemotherapy-induced thrombocytopenia

GA Soff, I Ray-Coquard, LJM Rivera, J Fryzek… - PLoS …, 2022 - journals.plos.org
Background Currently, there are no approved options to prevent or treat chemotherapy-
induced thrombocytopenia (CIT). We performed a systematic literature review and meta …

Hetrombopag for the management of chemotherapy-induced thrombocytopenia in patients with advanced solid tumors: a multicenter, randomized, double-blind …

S Qin, Y Wang, J Yao, Y Liu, T Yi… - Therapeutic …, 2024 - journals.sagepub.com
Background: Chemotherapy-induced thrombocytopenia (CIT) increases the risk of bleeding,
necessitates chemotherapy dose reductions and delays, and negatively impacts prognosis …

Romiplostim–A narrative drug review

A Gupta, A Kapoor, A Choudhary… - Cancer Research …, 2022 - journals.lww.com
Chemotherapy-induced thrombocytopenia (CIT) is a challenging condition that is routinely
encountered in oncology practice. Currently, the sole therapeutic modality for CIT is the …

Megakaryoblasts And Erythroblasts In Mice Bone Marrow After Gamma-irradiation With Sublethal Doses. Extracellular Ubiquitin Effect

RS Sujashvili, IV Ioramashvili - Radiobiology and Radiation Safety, 2023 - radiobiology.ge
Studies show that erythropoiesis and thrombopoiesis are interrelated. We provided
cytological and statistical analyses of elevation-depletion picks for megakaryocytes and …