Animal models to understand the etiology and pathophysiology of polycystic ovary syndrome

E Stener-Victorin, V Padmanabhan… - Endocrine …, 2020 - academic.oup.com
More than 1 out of 10 women worldwide are diagnosed with polycystic ovary syndrome
(PCOS), the leading cause of female reproductive and metabolic dysfunction. Despite its …

Evidence from animal models on the pathogenesis of PCOS

KA Walters, MJ Bertoldo, DJ Handelsman - Best Practice & Research …, 2018 - Elsevier
Polycystic ovarian syndrome (PCOS) is the most common endocrine condition in women,
and is characterized by reproductive, endocrine and metabolic features. However, there is …

Enlarged adipocytes from subcutaneous vs. visceral adipose tissue differentially contribute to metabolic dysfunction and atherogenic risk of patients with obesity

JA Suárez-Cuenca, G De La Peña-Sosa… - Scientific reports, 2021 - nature.com
Morphological characteristics and source of adipose tissue as well as adipokines may
increase cardiometabolic risk. This study aimed to explore whether adipose tissue …

[HTML][HTML] Efficacy of electroacupuncture in regulating the imbalance of AMH and FSH to improve follicle development and hyperandrogenism in PCOS rats

Y Shi, L Li, J Zhou, J Sun, L Chen, J Zhao, L Wu… - Biomedicine & …, 2019 - Elsevier
Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism and follicular
arrest. These two characteristics may result from an imbalance between anti-Müllerian …

Evaluation of changes in levels of hyperandrogenism, hirsutism and menstrual regulation after a period of aquatic high intensity interval training in women with …

Z Samadi, E Bambaeichi, M Valiani… - International journal of …, 2019 - journals.lww.com
Background: Polycystic ovary syndrome (PCOS) is a polygenic endocrine disorder in
women of reproductive ages which will lead to infertility. This study is aimed to determine …

White-brown adipose tissue interplay in polycystic ovary syndrome: Therapeutic avenues

K Abbasi, R Zarezadeh, A Valizadeh… - Biochemical …, 2024 - Elsevier
This study highlights the therapeutic potential of activating brown adipose tissue (BAT) for
managing polycystic ovary syndrome (PCOS), a prevalent endocrine disorder associated …

[HTML][HTML] Roxadustat alleviates metabolic traits in letrozole-induced PCOS mice

N Virtanen, U Saarela, M Karpale, RK Arffman… - Biochemical …, 2024 - Elsevier
Polycystic ovary syndrome (PCOS) is a highly prevalent disorder in women that is commonly
accompanied by metabolic syndrome. Activation of the hypoxia-inducible factor (HIF) …

Increased risk of eating disorders in women with polycystic ovary syndrome: a case-control study

B Başar Gökcen, Y Akdevelioğlu, S Canan… - Gynecological …, 2020 - Taylor & Francis
Data on eating disorders in women with PCOS is insufficient. The objective of this case study
was to examine the hypothesis that women with PCOS exhibit more impaired eating than …

[HTML][HTML] Photobiomodulation can improve ovarian activity in polycystic ovary syndrome-induced rats

ED Alves, ALO Bonfá, GR Pigatto… - … of Photochemistry and …, 2019 - Elsevier
Follicular cystic ovary disease is a common reproductive disorder in women and females of
domestic animals, characterized by anovulation and the persistence of follicle is a common …

Improving the accuracy and efficacy of diagnosing polycystic ovary syndrome by integrating metabolomics with clinical characteristics: study protocol for a randomized …

CM Ni, WL Huang, YM Jiang, J Xu, R Duan, YL Zhu… - Trials, 2020 - Springer
Background Polycystic ovary syndrome (PCOS) is a complex endocrine syndrome with
poorly understood mechanisms. To provide patients with PCOS with individualized therapy …