Knowledge about the role of the right ventricle in health and disease historically has lagged
behind that of the left ventricle. Less muscular, restricted in its role to pumping blood through …

The heart exhibits remarkable adaptive responses to a wide array of genetic and extrinsic
factors to maintain contractile function. When compensatory responses are not sustainable …

Nearly one-third of deaths in the United States are caused by cardiovascular disease (CVD)
each year. In the past, CVD was thought to mainly affect men, leading to the exclusion of …

Hypertrophic cardiomyopathy (HCM) is a common inherited cardiac disorder that
characterized by marked thickening of the left ventricular wall that occurs in the absence of …

The manifestations of cardiovascular diseases differ between men and women, as do
outcomes after therapeutic interventions. It is important that those involved in drug discovery …

This review discusses various issues to consider when developing standard operating
procedures for pre-clinical studies in the mdx mouse model of Duchenne muscular …

Approximately one-third of cancer deaths are caused by cachexia, a severe form of skeletal
muscle and adipose tissue wasting that affects men more than women. The heart also …

Biological sex plays an important role in normal cardiac physiology as well as in the heart's
response to cardiac disease. Women generally have better cardiac function and survival …

Hypertrophic cardiomyopathy (HCM) is the most common form of sudden death in young
competitive athletes. However, exercise has also been shown to be beneficial in the setting …

Biological sex plays an important role in normal cardiac physiology as well as in the heart's
response to cardiac disease. Women generally have better cardiac function and survival …