Structural insights into nuclear transcription by eukaryotic DNA-dependent RNA polymerases
The eukaryotic transcription apparatus synthesizes a staggering diversity of RNA molecules.
The labour of nuclear gene transcription is, therefore, divided among multiple DNA …
The labour of nuclear gene transcription is, therefore, divided among multiple DNA …
Metazoan promoters: emerging characteristics and insights into transcriptional regulation
Promoters are crucial for gene regulation. They vary greatly in terms of associated regulatory
elements, sequence motifs, the choice of transcription start sites and other features. Several …
elements, sequence motifs, the choice of transcription start sites and other features. Several …
[HTML][HTML] Epigenetics of stress adaptations in the brain
AM Stankiewicz, AH Swiergiel, P Lisowski - Brain research bulletin, 2013 - Elsevier
Recent findings in epigenetics shed new light on the regulation of gene expression in the
central nervous system (CNS) during stress. The most frequently studied epigenetic …
central nervous system (CNS) during stress. The most frequently studied epigenetic …
Two independent transcription initiation codes overlap on vertebrate core promoters
A core promoter is a stretch of DNA surrounding the transcription start site (TSS) that
integrates regulatory inputs and recruits general transcription factors to initiate transcription …
integrates regulatory inputs and recruits general transcription factors to initiate transcription …
Promoter shape varies across populations and affects promoter evolution and expression noise
Animal promoters initiate transcription either at precise positions (narrow promoters) or
dispersed regions (broad promoters), a distinction referred to as promoter shape. Although …
dispersed regions (broad promoters), a distinction referred to as promoter shape. Although …
Inter-embryo gene expression variability recapitulates the hourglass pattern of evo-devo
Background The evolution of embryological development has long been characterized by
deep conservation. In animal development, the phylotypic stage in mid-embryogenesis is …
deep conservation. In animal development, the phylotypic stage in mid-embryogenesis is …
Influence of rotational nucleosome positioning on transcription start site selection in animal promoters
The recruitment of RNA-Pol-II to the transcription start site (TSS) is an important step in gene
regulation in all organisms. Core promoter elements (CPE) are conserved sequence motifs …
regulation in all organisms. Core promoter elements (CPE) are conserved sequence motifs …
A CpG island promoter drives the CXXC5 gene expression
CXXC5 is a member of the zinc-finger CXXC family that binds to unmethylated CpG
dinucleotides. CXXC5 modulates gene expressions resulting in diverse cellular events …
dinucleotides. CXXC5 modulates gene expressions resulting in diverse cellular events …
Nucleosome-specific, time-dependent changes in histone modifications during activation of the early growth response 1 (Egr1) gene
ÁL Riffo-Campos, J Castillo, G Tur… - Journal of Biological …, 2015 - ASBMB
Histone post-translational modifications and nucleosome remodeling are coordinate events
involved in eukaryotic transcriptional regulation. There are relatively few data on the time …
involved in eukaryotic transcriptional regulation. There are relatively few data on the time …
Gene expression classification using epigenetic features and DNA sequence composition in the human embryonic stem cell line H1
WX Su, QZ Li, LQ Zhang, GL Fan, CY Wu, ZH Yan… - Gene, 2016 - Elsevier
Epigenetic factors are known to correlate with gene expression in the existing studies.
However, quantitative models that accurately classify the highly and lowly expressed genes …
However, quantitative models that accurately classify the highly and lowly expressed genes …