Clinical applications and anticancer effects of antimicrobial peptides: from bench to bedside

A Jafari, A Babajani, R Sarrami Forooshani… - Frontiers in …, 2022 - frontiersin.org
Cancer is a multifaceted global health issue and one of the leading causes of death
worldwide. In recent years, medical science has achieved great advances in the diagnosis …

A comprehensive review about the molecular structure of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): Insights into natural products against …

EM Saied, YA El-Maradny, AA Osman, AMG Darwish… - Pharmaceutics, 2021 - mdpi.com
In 2019, the world suffered from the emergence of COVID-19 infection, one of the most
difficult pandemics in recent history. Millions of confirmed deaths from this pandemic have …

Scorpion peptide Smp24 exhibits a potent antitumor effect on human lung cancer cells by damaging the membrane and cytoskeleton in vivo and in vitro

R Guo, J Liu, J Chai, Y Gao, MA Abdel-Rahman, X Xu - Toxins, 2022 - mdpi.com
Smp24, a cationic antimicrobial peptide identified from the venom gland of the Egyptian
scorpion Scorpio maurus palmatus, shows variable cytotoxicity on various tumor (KG1a …

Antimicrobial Peptides: Source, application and recent developments

D Chettri, A Rani, B Sharma, M Selvaraj, MA Assiri… - Process …, 2024 - Elsevier
Antimicrobial peptides (AMPs) belong to a group of biomolecules found in various life forms
and form an important part of their defense mechanisms. They are effective against bacteria …

Antitumor effects of scorpion peptide Smp43 through mitochondrial dysfunction and membrane disruption on hepatocellular carcinoma

J Chai, W Yang, Y Gao, R Guo, Q Peng… - Journal of natural …, 2021 - ACS Publications
Smp43, a cationic antimicrobial peptide identified from the venom gland of the Egyptian
scorpion Scorpio maurus palmatus, shows cytotoxicity toward hepatoma cell line HepG2 by …

Bioprocess Optimization of Nutritional Parameters for Enhanced Anti-leukemic L-Asparaginase Production by Aspergillus candidus UCCM 00117: A Sequential …

M Ekpenyong, A Asitok, R Antigha, N Ogarekpe… - International Journal of …, 2021 - Springer
Sequential optimization of bioprocess nutritional conditions for production of glutaminase-
near-free L-asparaginase by Aspergillus candidus UCCM 00117 was conducted under …

Scorpion venom antimicrobial peptides induce caspase-1 dependant pyroptotic cell death

RA Elrayess, ME Mohallal, YM Mobarak… - Frontiers in …, 2022 - frontiersin.org
Within the last decade, several peptides have been identified according to their ability to
inhibit the growth of microbial pathogens. These antimicrobial peptides (AMPs) are a part of …

Cytotoxicity and molecular alterations induced by scorpion venom antimicrobial peptide Smp43 in breast cancer cell lines MDA-MB-231 and MCF-7

WK Teleb, MA Tantawy, X Xu, AA Hussein… - International journal of …, 2022 - Springer
Smp43 is a novel cationic antimicrobial peptide (AMP) which was extracted from the venom
of Scorpio maurus palmatus scorpion. However, many studies described the cytotoxic …

Mesenchymal stem cell-derived antimicrobial peptides as potential anti-neoplastic agents: new insight into anticancer mechanisms of stem cells and exosomes

K Moeinabadi-Bidgoli, M Rezaee… - Frontiers in Cell and …, 2022 - frontiersin.org
Mesenchymal stem cells (MSCs), as adult multipotent cells, possess considerable
regenerative and anti-neoplastic effects, from inducing apoptosis in the cancer cells to …

Investigating the inhibitory and penetrating properties of three novel anticancer and antimicrobial scorpion peptides via molecular docking and molecular dynamic …

E Jahangirian, J Zargan, H Rabbani… - Journal of Biomolecular …, 2023 - Taylor & Francis
The two types of bladder cancer, muscle invasive and non-muscle invasive (NMIBC), are
among the most prevalent cancers worldwide. Despite this, even though muscle-invasive …