Hypomyelination, hypodontia and craniofacial abnormalities in a Polr3b mouse model of leukodystrophy

MA Michell-Robinson, KEN Watt, V Grouza… - Brain, 2023 - academic.oup.com
Abstract RNA polymerase III (Pol III)-related hypomyelinating leukodystrophy (POLR3-HLD),
also known as 4H leukodystrophy, is a severe neurodegenerative disease characterized by …

Myelin basic protein mRNA levels affect myelin sheath dimensions, architecture, plasticity, and density of resident glial cells

H Bagheri, H Friedman, A Hadwen, C Jarweh… - …, 2024 - portal.findresearcher.sdu.dk
Myelin basic protein (Mbp) is essential for both elaboration and maintenance of CNS myelin,
and its reduced accumulation results in hypomyelination. How different Mbp mRNA levels …

[HTML][HTML] Ultra-high-resolution mapping of myelin and g-ratio in a panel of Mbp enhancer-edited mouse strains using microstructural MRI

V Grouza, H Bagheri, H Liu, M Tuznik, Z Wu… - NeuroImage, 2024 - Elsevier
Non-invasive myelin water fraction (MWF) and g-ratio mapping using microstructural MRI
have the potential to offer critical insights into brain microstructure and our overall …

Deep Dive into MRI: Exploring Deep Learning Applications in 0.55 T and 7T MRI

AC Alves, A Ferreira, B Puladi, J Egger… - arXiv preprint arXiv …, 2024 - arxiv.org
The development of magnetic resonance imaging (MRI) for medical imaging has provided a
leap forward in diagnosis, providing a safe, non-invasive alternative to techniques involving …

[PDF][PDF] Myelin basic protein mRNA levels affect myelin sheath dimensions, architecture, plasticity, and density of resident glial cells

AC Peterson - 2024 - researchgate.net
Abstract Myelin Basic Protein (MBP) is essential for both elaboration and maintenance of
CNS myelin, and its reduced accumulation results in hypomyelination. How different Mbp …