Context.—Endobronchial ultrasound–guided transbronchial needle aspiration (EBUS-
TBNA) has emerged as a very useful tool in the field of diagnostic respiratory cytology …

With an escalating number of predictive biomarkers emerging in non–small cell lung
carcinoma (NSCLC), immunohistochemistry (IHC) is being used as a rapid and cost …

Since the 2015 WHO classification was introduced into clinical practice,
immunohistochemistry (IHC) has figured prominently in lung cancer diagnosis. In addition to …

Abstract Background PD-L1 immunohistochemistry (IHC) testing is usually carried out on
tissue blocks from core needle biopsy or surgical resections. In this study, we assessed the …

The fourth part of the European Federation of Societies for Ultrasound in Medicine and
Biology (EFSUMB) Guidelines on Interventional Ultrasound describes general aspects of …

The pathological and molecular classification of lung cancer has become substantially more
complex over the past decade. For diagnostic purposes on small samples, additional stains …

The cell block (CB) offers many advantages over other cytological preparations, particularly
for immunocytochemical and molecular testing. However, inconsistent cellularity remains the …

Objective: The cell block (CB) technique refers to the processing of sediments, blood clots,
or grossly visible tissue fragments from cytological specimens into paraffin blocks that can …

The advent of targeted therapy in lung cancer has heralded a paradigm shift in the practice
of cytopathology with the need for accurately subtyping lung carcinoma, as well as providing …

Context.—There has been a paradigm shift in the understanding of molecular pathogenesis
of lung cancer. A number of oncogenic drivers have been identified in non–small cell lung …