Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

Diabetes Mellitus (DM) is a complex metabolic disorder associated with multiple
microvascular complications leading to nephropathy, retinopathy, and neuropathy. Mounting …

Canine babesiosis is a tick-borne protozoan disease caused by intraerythrocytic parasites of
the genus Babesia. The infection may lead to anemia in infected dogs. However, anemia is …

Cell membrane lipid composition, especially cholesterol, affects many functions of
embedded enzymes, transporters and receptors in red blood cells (RBC). High membrane …

Eukaryotic cells are defined as cells containing distinct nuclei and other membranous
organelles. However, red blood cells (RBCs) lack a nucleus and organelles—perhaps to …

Introduction: High-altitude polycythemia (HAPC) is a common chronic high-altitude disease
characterized by significantly increased erythrocyte, hemoglobin (Hb), and hematocrit …

Hypoxia is caused by insufficient oxygen availability for the organism leading to reduced
oxygen delivery to tissues and cells. It has been regarded as a severe threat to human …

Emerging studies provide new data shedding some light on the complex and pivotal role of
red blood cells (RBCs) in nitric oxide (NO) metabolism and paracrine regulation of …

Intracellular delivery of freezing‐tolerant trehalose is crucial for cryopreservation of red
blood cells (RBCs) and previous strategies based on membrane‐disruptive activity usually …

Chemotherapy-related anemia is a major obstacle in anticancer therapy. Tamoxifen (TAM) is
an antiestrogen prescribed for breast cancer patients with hemolytic potential and apoptotic …