A comprehensive review on C-3 functionalization of β-lactams

R Nagpal, J Bhalla, SS Bari - Current Organic Synthesis, 2019 - ingentaconnect.com
Background: A lot of advancement has been made in the area of β-lactams in recent times.
Most of the research is targeted towards the synthesis of novel β-lactams, their …

Stereoselective synthesis and characterization of novel trans-4-(thiophenyl) pyrazolyl-β-lactams and their C–3 functionalization

P Saini, SS Bari, SC Sahoo, S Khullar, SK Mandal… - Tetrahedron, 2019 - Elsevier
A stereoselective synthesis and C–3 functionalization of a long series of novel hybrid 4-
(thiophenyl) pyrazolyl-β-lactams have been carried out. The divergent substrate scope and …

Synthesis of α‐Heterocycle Anchored Spirocyclic Azetidin‐2‐ones in a Minute by p‐TSA Catalyzed Cyclocondensation of Azetidin‐2,3‐diones with Difunctionalized …

D Narula, SS Bari, P Yadav, S Khullar… - …, 2021 - Wiley Online Library
Abstract Monocyclic azetidin‐2, 3‐diones provide easy extensions to spiro‐fused azetidin‐2‐
ones upon p‐toluenesulfonic acid (p‐TSA) catalyzed cyclocondensation reaction with …

Stereoselective synthesis of trans-3-functionalized-4-pyrazolo[5,1-b]thiazole-3-carboxylate substituted β-lactams: Potential synthons for diverse biologically active …

S Berry, SS Bari, P Yadav, A Garg… - Synthetic …, 2020 - Taylor & Francis
An efficient protocol for the stereoselective synthesis of pyrazolo [5, 1-b] thiazole-3-
carboxylate tethered β-lactam conjugates 8a–j from novel pyrazolo [5, 1-b] thiazole-3 …

Comprehensive study towards the desulfonylation/desulfinylation of cis-3-functionalized 3-phenylsulfonyl/sulfinyl-β-lactams to access novel cis-3-monosubstituted-β …

A Kumari, SS Bari, G Modi, S Berry, S Khullar… - Tetrahedron, 2018 - Elsevier
An inclusive study towards the stereospecific synthesis of novel cis-3-monosubstituted-β-
lactams from cis-3-functionalized 3-phenylsulfonyl/sulfinyl-β-lactams is described. 3-Sulfinyl …

Stereoselective synthesis, characterization and mechanistic insights of ortho-/meta-/para-(2-benzo[d]oxazolyl)phenyl substituted trans-β-lactams: Potential …

P Saini, SS Bari, S Thakur, A Garg… - Synthetic …, 2022 - Taylor & Francis
The present work describes the synthesis of novel ortho-, meta-and para-(2-benzo [d]
oxazolyl) phenyl-β-lactams 5 using isomeric (ortho-, meta-and para-)(2-beno [d] oxazolyl) …

A highly stereoselective oxidation and an easy one pot elimination methodology for 3-allyl-3-phenylthio-β-lactams

S Pandey, R Nagpal, A Thakur, SS Bari… - Journal of Sulfur …, 2022 - Taylor & Francis
A novel, facile, highly efficient and stereoselective protocol for the synthesis of cis-3-allyl-3-
phenylsulfinyl-β-lactams and 3-allylidene-β-lactams from cis-3-allyl-3-phenylthio-β-lactams …

Design, Synthesis, DNA Binding, Cytotoxicity, and Molecular Docking Studies of Amonafide‐Linked β‐Lactam

JA Rad, A Jarrahpour, MD Aseman… - …, 2019 - Wiley Online Library
This study describes our investigations on the synthesis, molecular modeling, and biological
capabilities of a new β‐lactam containing the anticancer agent, amonafide. This is the first …

An investigation towards the diastereoselective synthesis of 3-acetoxy/methoxy/phthalimido-β-lactams using chiral imines

A Bhalla, G Modi, SS Bari, A Kumari, D Narula… - Tetrahedron …, 2017 - Elsevier
The efficient diastereoselective synthesis of 3-acetoxy/methoxy/phthalimido-β-lactams 2/2′,
3/3′ and 4/4′ respectively was performed using chiral imines 1 obtained from chiral …

Stereoselective synthesis of novel monocyclic trans-3-halogenated-4-pyrazolyl-β-lactams: Potential synthons and promising biologically active agents

S Berry, SS Bari, BK Banik, A Bhalla - Synthetic Communications, 2017 - Taylor & Francis
Stereoselective synthesis of novel monocyclic trans-3-halogenated-4-pyrazolyl-β-lactams 5
is described. The reaction of ketene derived from α-bromo/chloroethanoic acids 4 using …