[HTML][HTML] Non-small cell lung carcinoma (NSCLC): Implications on molecular pathology and advances in early diagnostics and therapeutics

H Padinharayil, J Varghese, MC John, GK Rajanikant… - Genes & …, 2023 - Elsevier
Continuous revision of the histologic and stage-wise classification of lung cancer by the
World Health Organization (WHO) provides the foundation for therapeutic advances by …

[HTML][HTML] Molecular biomarkers in early stage lung cancer

M Rodríguez, D Ajona, LM Seijo, J Sanz… - … lung cancer research, 2021 - ncbi.nlm.nih.gov
Low dose computed tomography (LDCT) screening, together with the recent advances in
targeted and immunotherapies, have shown to improve non-small cell lung cancer (NSCLC) …

Integrated Clinical-Molecular classification of Colorectal Liver metastases: a biomarker analysis of the phase 3 New EPOC Randomized Clinical Trial

RR Katipally, CA Martinez, SA Pugh… - JAMA …, 2023 - jamanetwork.com
Importance Personalized treatment approaches for patients with oligometastatic colorectal
liver metastases are critically needed. We previously defined 3 biologically distinct …

Update on adjuvant therapy in completely resected NSCLC patients

JU Lim, CD Yeo - Thoracic Cancer, 2022 - Wiley Online Library
In patients with completely resected non‐small cell lung cancer (NSCLC), postoperative
adjuvant chemotherapy has been associated with improvement in survival by minimizing the …

[HTML][HTML] Multi-institutional prospective validation of prognostic mRNA signatures in early stage squamous lung cancer (alliance)

R Bueno, WG Richards, DH Harpole… - Journal of Thoracic …, 2020 - Elsevier
Introduction Surgical resection is curative for some patients with early lung squamous cell
carcinoma. Staging and clinical factors do not adequately predict recurrence risk. We sought …

Incorporation of the lepidic component as an additional pathological T descriptor for non-small cell lung cancer: Data from 3335 cases of lung adenocarcinoma

S Huang, M Zhao, S Li, T Chen, Y Zhong, J Deng, L Xu… - Lung Cancer, 2024 - Elsevier
Abstract Objectives The Lepidic Component (LP) identifies a subgroup with an excellent
prognosis for lung adenocarcinoma (LUAD). Our research aimed to propose an improved …

AI-Enabled Lung Cancer Prognosis

M Darvish, R Trask, P Tallon, M Khansari, L Ren… - arXiv preprint arXiv …, 2024 - arxiv.org
Lung cancer is the primary cause of cancer-related mortality, claiming approximately 1.79
million lives globally in 2020, with an estimated 2.21 million new cases diagnosed within the …

Comparison of conventional TNM and novel TNMB staging systems for non–small cell lung cancer

GJ Haro, B Sheu, NR Cook, GA Woodard… - JAMA Network …, 2019 - jamanetwork.com
Importance Improved staging for non–small cell lung cancer (NSCLC) represents a critical
unmet need. External validations of the eighth edition of the TNM staging system have …

Effect of epidermal growth factor receptor gene mutation on the prognosis of pathological stage II–IIIA (TNM classification) primary lung cancer after curative surgery

T Isaka, H Ito, H Nakayama, T Yokose, H Saito… - Lung Cancer, 2021 - Elsevier
Objectives This retrospective study aimed to elucidate the effect of epidermal growth factor
receptor (EGFR) gene mutations on the prognosis of patients with pathological stage II–IIIA …

Genetic and immunologic features of recurrent stage I lung adenocarcinoma

JR Kratz, JZ Li, J Tsui, JC Lee, VW Ding, AA Rao… - Scientific reports, 2021 - nature.com
Although surgery for early-stage lung cancer offers the best chance of cure, recurrence still
occurs between 30 and 50% of the time. Why patients frequently recur after complete …