The cerebellum governs motor coordination and motor learning. Infection with external
microorganisms, such as viruses, bacteria, and fungi, induces the release and production of …

Simple Summary Impairment of the immune-barrier system in the aged brain is manifested
in neurodegenerative diseases, such as Alzheimer's disease. Cerebrospinal fluid flow and …

Recently, we identified biallelic mutations of SLC25A46 in patients with multiple
neuropathies. Functional studies revealed that SLC25A46 may play an important role in …

Lipopolysaccharide (LPS), an outer component of Gram-negative bacteria, induces a strong
response of innate immunity via microglia, which triggers a modulation of the intrinsic …

Background Purkinje cells play a central role in establishing the cerebellar circuit.
Accordingly, disrupting Purkinje cell development impairs cerebellar morphogenesis and …

The deteriorating effects of Lead (Pb) on central nervous system (CNS) such as cerebellum
has been demonstrated in previous studies. Glycoconjugates with the important role in CNS …

The cerebellar germ arises from the rhombic lip, and it's a rostral part from the
mesencephalon. The following cellular processes take place in the developing cerebellum …

Lipopolysaccharide (LPS), an outer component of Gram-negative bacteria, induces a strong
response of innate immunity via microglia, which triggers a modulation of the intrinsic …

The lymphatic system is important for antigen presentation and immune surveillance. The
lymphatic system in the brain was originally introduced by Giovanni Mascagni in 1787, while …

Throughout his career, Enrico Mugnaini has been an outstanding neuromorphologist, a
generous colleague, and a very knowledgeable and skillful tutor (Fig 1). He did excellent …