Duchenne muscular dystrophy (DMD) is a progressive disease caused by the loss of
function of the protein dystrophin. This protein contributes to the stabilisation of striated cells …

It is generally accepted that skeletal muscle fiber hypertrophy in response to loading is a
consequence of individual muscle fiber growth, and not the creation of de novo muscle …

The role of tissue-resident macrophages during tissue regeneration or fibrosis is not well
understood, mainly due to the lack of a specific marker for their identification. Here, we …

The function of many organs, including skeletal muscle, depends on their three-dimensional
structure. Muscle regeneration therefore requires not only reestablishment of myofibers but …

Satellite cells (SCs) are the main muscle stem cells responsible for its regenerative capacity.
In muscular dystrophies, however, a failure of the regenerative process results in muscle …

Introduction: It has been proposed that an increased susceptivity to oxidative stress caused
by the absence of the protein dystrophin from the inner surface of the sarcolemma is a …

The muscular dystrophy X-linked mouse (mdx) is the most commonly used preclinical model
for Duchenne muscular dystrophy. Although disease progression in the mouse does not …

Duchenne muscular dystrophy is caused by the absence of the protein dystrophin from
skeletal muscle and is characterized by progressive cycles of necrosis/regeneration. Using …

Rationale: Structural remodeling or damage as a result of disease or injury is often not
evenly distributed throughout a tissue but strongly depends on localization and extent of …

Duchenne muscular dystrophy (DMD) is the second most common fatal genetic disease in
humans and is characterized by the absence of a functional copy of the protein dystrophin …