[HTML][HTML] Glial cells shape pathology and repair after spinal cord injury

AD Gaudet, LK Fonken - Neurotherapeutics, 2018 - Elsevier
Glial cell types were classified less than 100 years ago by del Rio-Hortega. For instance, he
correctly surmised that microglia in pathologic central nervous system (CNS) were …

Myelin status and oligodendrocyte lineage cells over time after spinal cord injury: What do we know and what still needs to be unwrapped?

N Pukos, MT Goodus, FR Sahinkaya, DM McTigue - Glia, 2019 - Wiley Online Library
Spinal cord injury (SCI) affects over 17,000 individuals in the United States per year,
resulting in sudden motor, sensory and autonomic impairments below the level of injury …

Extracellular matrix and oxidative stress following traumatic spinal cord injury: physiological and pathophysiological roles and opportunities for therapeutic intervention

JCT Chio, N Punjani, N Hejrati… - Antioxidants & redox …, 2022 - liebertpub.com
Significance: Traumatic spinal cord injury (SCI) causes significant disruption to neuronal,
glial, vascular, and extracellular elements. The spinal cord extracellular matrix (ECM) …

Emerging targets for reprograming the immune response to promote repair and recovery of function after spinal cord injury

FH Brennan, PG Popovich - Current opinion in neurology, 2018 - journals.lww.com
Emerging targets for reprograming the immune response to pro... : Current Opinion in Neurology
Emerging targets for reprograming the immune response to promote repair and recovery of …

The dual role of hepcidin in brain iron load and inflammation

D Vela - Frontiers in Neuroscience, 2018 - frontiersin.org
Hepcidin is the major regulator of systemic iron metabolism, while the role of this peptide in
the brain has just recently been elucidated. Studies suggest a dual role of hepcidin in …

The hallmark and crosstalk of immune cells after intracerebral hemorrhage: Immunotherapy perspectives

W Zhang, Q Wu, S Hao, S Chen - Frontiers in Neuroscience, 2023 - frontiersin.org
Intracerebral hemorrhage (ICH) is one of the most dangerous types of strokes with a high
morbidity and mortality rate. Currently, the treatment of ICH is not well developed, mainly …

MAPK: a key player in the development and progression of stroke

Y Zheng, Z Han, H Zhao, Y Luo - CNS & Neurological …, 2020 - ingentaconnect.com
Stroke is a complex disease caused by genetic and environmental factors, and its etiological
mechanism has not been fully clarified yet, which brings great challenges to its effective …

Oligodendrocytes in intracerebral hemorrhage

M Kang, Y Yao - CNS neuroscience & therapeutics, 2019 - Wiley Online Library
Intracerebral hemorrhage (ICH) is a cerebrovascular disorder with high mortality and
disability rates. Although a lot of effort has been put in ICH, there is still no effective treatment …

Iron toxicity in intracerebral hemorrhage: physiopathological and therapeutic implications

Y Wei, X Song, Y Gao, Y Gao, Y Li, L Gu - Brain Research Bulletin, 2022 - Elsevier
Intracerebral hemorrhage (ICH)-induced brain injury is a continuous pathological process
that involves the deterioration of neurological functions, such as sensory, cognitive or motor …

Harpagophytum procumbens Inhibits Iron Overload‐Induced Oxidative Stress through Activation of Nrf2 Signaling in a Rat Model of Lumbar Spinal Stenosis

JY Hong, H Kim, J Lee, WJ Jeon… - … Medicine and Cellular …, 2022 - Wiley Online Library
Lumbar spinal stenosis (LSS) is a common degenerative spinal condition in older
individuals that causes impaired walking and other disabilities due to severe lower back and …