How the shape of embryos and organs emerges during development is a fundamental
question that has fascinated scientists for centuries. Tissue dynamics arise from a small set …

The fascinating patterns of collective motion created by autonomously driven particles have
fuelled active-matter research for over two decades. So far, theoretical active-matter …

Biomolecular and physical cues of the extracellular matrix environment regulate collective
cell dynamics and tissue patterning. Nonetheless, how the viscoelastic properties of the …

We review recent evidence showing that cell and tissue dynamics are governed by
mesoscale physical principles. These principles can be understood in terms of simple state …

Prostate cancer (PCa) is a prevalent malignancy that occurs primarily in old males. Prostate
tumors in different patients manifest significant inter-patient heterogeneity with respect to …

Epithelial branch elongation is a central developmental process during branching
morphogenesis in diverse organs. This fundamental growth process into large arborized …

Self-organization is pervasive in development, from symmetry breaking in the early embryo
to tissue patterning and morphogenesis. For a few model systems, the underlying molecular …

Human cholangiocyte organoids show great promise for regenerative therapies and in vitro
modeling of bile duct development and diseases. However, the cystic organoids lack the …

The development dynamics and self-organization of glandular branched epithelia is of
utmost importance for our understanding of diverse processes ranging from normal tissue …

The silica-based cell walls of diatoms are prime examples of genetically controlled, species-
specific mineral architectures. The physical principles underlying morphogenesis of their …