Drug resistant tuberculosis: Implications for transmission, diagnosis, and disease management

D Liebenberg, BG Gordhan, BD Kana - Frontiers in cellular and …, 2022 - frontiersin.org
Drug resistant tuberculosis contributes significantly to the global burden of antimicrobial
resistance, often consuming a large proportion of the healthcare budget and associated …

Functions of exosomal non-coding RNAs to the infection with Mycobacterium tuberculosis

J Wang, Y Li, N Wang, J Wu, X Ye, Y Jiang… - Frontiers in …, 2023 - frontiersin.org
Tuberculosis (TB) is a major infectious disease induced by Mycobacterium tuberculosis (M.
tb) which causes the world's dominant fatal bacterial contagious disease. Increasing studies …

Facilitating the use of the target product profile in academic research: a systematic review

A Ibnidris, N Liaskos, E Eldem, A Gunn… - Journal of Translational …, 2024 - Springer
Abstract Background The Target Product Profile (TPP) is a tool used in industry to guide
development strategies by addressing user needs and fostering effective communication …

Use of point-of-care C-reactive protein testing for screening of tuberculosis in the community in high-burden settings: a prospective, cross-sectional study in Zambia …

M Ruperez, K Shanaube, L Mureithi… - The Lancet Global …, 2023 - thelancet.com
Background WHO recommends community-wide, systematic tuberculosis screening in high-
prevalence settings. C-reactive protein has been proposed as a tuberculosis screening tool …

The performance of tongue swabs for detection of pulmonary tuberculosis

CS Ealand, A Sewcharran, JS Peters… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction Oral and/or tongue swabs have demonstrated ability to detect Mycobacterium
tuberculosis (Mtb) in adults with pulmonary tuberculosis (TB). Swabs provide useful …

Point-of-care C-reactive protein and Xpert MTB/RIF Ultra for tuberculosis screening and diagnosis in unselected antiretroviral therapy initiators: a prospective, cross …

BWP Reeve, G Ndlangalavu, H Mishra… - The Lancet Global …, 2024 - thelancet.com
Background Tuberculosis, a major cause of death in people living with HIV, remains
challenging to diagnose. Diagnostic accuracy data are scarce for promising triage and …

Mycosome-Coated Gold Nanoparticles for Plasmonic Detection of Tuberculosis-Associated Antibodies

AH Becerra, MG Flores, JP Palma-Nicolas… - ACS Applied Nano …, 2024 - ACS Publications
Considering that more than 10 million people develop tuberculosis disease (TB) each year
and that nearly 3 million of them are never diagnosed, label-free screening methods …

C1q and HBHA-specific IL-13 levels as surrogate plasma biomarkers for monitoring tuberculosis treatment efficacy: a cross-sectional cohort study in Paraguay

G Russomando, D Sanabria, CC Díaz Acosta… - Frontiers in …, 2024 - frontiersin.org
Introduction New diagnostic tools are needed to rapidly assess the efficacy of pulmonary
tuberculosis (PTB) treatment. The aim of this study was to evaluate several immune …

PneumoniaCheck, a novel aerosol collection device, permits capture of airborne Mycobacterium tuberculosis and characterisation of the cough aeromicrobiome in …

TL Chiyaka, GR Nyawo, CC Naidoo, S Moodley… - Annals of Clinical …, 2024 - Springer
Background Tuberculosis (TB), a major cause of disease and antimicrobial resistance, is
spread via aerosols. Aerosols have diagnostic potential and airborne-microbes other than …

Clinically Relevant Metallic Nanoparticles in Tuberculosis Diagnosis and Therapy

CA Akinnawo, A Dube - Advanced Therapeutics, 2024 - Wiley Online Library
Globally a significant burden of tuberculosis (TB) is faced, which is difficult to eradicate due
to patients' non‐adherence, and drug‐resistant strains that are spreading at an alarming …