Arterial remodeling refers to the structural and functional changes of the vessel wall that
occur in response to disease, injury, or aging. Vascular smooth muscle cells (VSMC) play a …

Endothelial cells (ECs) that reside on the surface of blood vessels are constantly exposed to
mechanical stimulation, including shear stress. Fluid shear stress (FSS) controls multiple …

Aneurysms are malformations within the arterial vasculature brought on by the structural
breakdown of the microarchitecture of the vessel wall, with aneurysms posing serious health …

Introduction Intracellular reactive oxygen species (ROS) and nitric oxide (NO) levels are
associated with vascular homeostasis and diseases. Exercise can modulate ROS and NO …

Recently, nanomedicines have gained a great deal of attention in diverse biomedical
applications, including anti-cancer therapy. Being different from normal tissue, the …

Rationale: The spine is one of the most common metastatic sites of non-small cell lung
cancer (NSCLC), and NSCLC spinal metastasis results in serious consequences. Metastatic …

To reproduce hemodynamic stress microenvironments of endothelial cells in vitro is of vital
significance, by which one could exploit the quantitative impact of hemodynamic stresses on …

The most common non-pharmacological intervention for both peripheral and cerebral
vascular health is regular physical activity (eg, exercise training), which improves function …

The vascular endothelial cells constitute the innermost layer. The cells are exposed to
mechanical stress by the flow, causing them to express their functions. To elucidate the …

Generating precise in vivo arterial endothelial hemodynamic microenvironments using
microfluidics is essential for exploring endothelial mechanobiology. However, a …