PKM2, function and expression and regulation

Z Zhang, X Deng, Y Liu, Y Liu, L Sun, F Chen - Cell & bioscience, 2019 - Springer
Pyruvate kinase (PK), as one of the key enzymes for glycolysis, can encode four different
subtypes from two groups of genes, although the M2 subtype PKM2 is expressed mainly …

[PDF][PDF] Circular RNA sequencing identifies CircASAP1 as a key regulator in hepatocellular carcinoma metastasis

ZQ Hu, SL Zhou, J Li, ZJ Zhou, PC Wang, HY Xin… - …, 2020 - Wiley Online Library
Background and Aims There is growing evidence that single‐stranded, circular RNA
(circRNA) plays a key role in the development of certain cancers, including hepatocellular …

The role and mechanism of β‑arrestins in cancer invasion and metastasis

Q Song, Q Ji, Q Li - International journal of molecular …, 2018 - spandidos-publications.com
Abstract β‑arrestins are a family of adaptor proteins that regulate the signaling and trafficking
of various G protein‑coupled receptors (GPCRs). They consist of β‑arrestin1 and β‑arrestin2 …

Circular RNA hsa_circ_0061825 (circ‐TFF1) contributes to breast cancer progression through targeting miR‐326/TFF1 signalling

G Pan, A Mao, J Liu, J Lu, J Ding, W Liu - Cell proliferation, 2020 - Wiley Online Library
Abstract Objectives Circular RNAs (circRNAs) are RNA transcripts that belong to non‐coding
RNAs (ncRNAs), whose implication in human cancers has been recently demonstrated …

Linc00152 promotes malignant progression of glioma stem cells by regulating miR-103a-3p/FEZF1/CDC25A pathway

M Yu, Y Xue, J Zheng, X Liu, H Yu, L Liu, Z Li, Y Liu - Molecular cancer, 2017 - Springer
Background Glioma is one of the most frequent intracranial malignant tumors. LncRNAs
have been identified as new modulators in the origination and progression of glioma …

A two-circular RNA signature as a noninvasive diagnostic biomarker for lung adenocarcinoma

XX Liu, YE Yang, X Liu, MY Zhang, R Li, YH Yin… - Journal of translational …, 2019 - Springer
Abstract Background Recently, circular RNAs (circRNAs) have been reported to be
microRNA sponges and play essential roles in cancer development. This study aimed to …

Targeting HIF1-alpha/miR-326/ITGA5 axis potentiates chemotherapy response in triple-negative breast cancer

R Assidicky, UM Tokat, IO Tarman, O Saatci… - Breast cancer research …, 2022 - Springer
Purpose Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast
cancer that is frequently treated with chemotherapy. However, many patients exhibit either …

Reactivation of tumour suppressor in breast cancer by enhancer switching through NamiRNA network

Y Liang, Q Lu, W Li, D Zhang, F Zhang… - Nucleic acids …, 2021 - academic.oup.com
Abstract Dysfunction of Tumour Suppressor Genes (TSGs) is a common feature in
carcinogenesis. Epigenetic abnormalities including DNA hypermethylation or aberrant …

MiR-326: promising biomarker for cancer

YJ Pan, J Wan, CB Wang - Cancer Management and Research, 2019 - Taylor & Francis
MicroRNAs (miRNAs) are small non-coding and highly conserved RNAs that act in
biological processes including cell proliferation, invasion, apoptosis, metabolism, signal …

Purified sulforaphane from broccoli (Brassica oleracea var. italica) leads to alterations of CDX1 and CDX2 expression and changes in miR-9 and miR-326 levels in …

S Kiani, H Akhavan-Niaki, S Fattahi, S Kavoosian… - Gene, 2018 - Elsevier
Background Genetic alterations and epigenetic modifications are two main factors involved
in gastric carcinogenesis, progression, and metastasis. Several miRNAs such as miRNA-9 …