Hepatitis C virus lymphotropism: lessons from a decade of studies

AL Zignego, C Giannini, M Monti, L Gragnani - Digestive and Liver Disease, 2007 - Elsevier
The possibility that HCV infects lymphoid cells has been widely discussed. Evidence in favor
of HCV tropism for lymphoid cells derives from a series of data including:(1) the higher …

Polysubstituted pyrazoles, part 5. Synthesis of new 1-(4-chlorophenyl)-4-hydroxy-1H-pyrazole-3-carboxylic acid hydrazide analogs and some derived ring systems. A …

SAF Rostom, MA Shalaby, MA El-Demellawy - European Journal of …, 2003 - Elsevier
A novel series of 1-(4-chlorophenyl)-4-hydroxy-1H-pyrazole-3-carboxylic acid hydrazide
analogs and some derived 4-substituted-1, 2, 4-triazolin-3-thiones, 2-substituted-1, 3, 4 …

Antibacterial and anticancer activity of marine Streptomyces parvus: optimization and application

H Abd-Elnaby, G Abo-Elala… - Biotechnology & …, 2016 - Taylor & Francis
ABSTRACT A total of 17 actinomycetes were isolated and screened against five bacterial
pathogens. Forty-one per cent of the isolates were active against the tested pathogens. The …

Cyanoacetic acid hydrazones of 3‐(and 4‐) Acetylpyridine and some derived ring systems as potential antitumor and anti‐HCV agents

SAM El‐Hawash, AE Abdel Wahab… - … der Pharmazie: An …, 2006 - Wiley Online Library
Two new acetylpyridinehydrazones derived from cyanoacetic acid hydrazide have been
synthesized namely: cyanoacetic acid (1‐pyridin‐3 or 4‐yl‐ethylidene) hydrazides (1a, b) …

[HTML][HTML] Hepatitis C virus RNA strands detection in peripheral blood mononuclear cells legitimizes virus eradication in negative serum PCR naïve and post-treatment …

MDA Abd Alla, MK El Awady - Journal of Clinical and Translational …, 2017 - ncbi.nlm.nih.gov
Abstract Background and Aims: Hepatitis C virus (HCV) hepatotropism is associated with
intra-peripheral blood mononuclear cell (PBMC) infection that causes post-treatment relapse …

Ten year incidence of HCV infection in northern Italy and frequency of spontaneous viral clearance

C Mazzeo, F Azzaroli, S Giovanelli, A Dormi, D Festi… - Gut, 2003 - gut.bmj.com
Background: Little is known of the incidence of hepatitis C virus (HCV) infection, and the
frequency of spontaneous viral clearance in the general population is unknown. We …

[PDF][PDF] Skin manifestations of chronic hepatitis C virus infection in Cairo, Egypt

HMZ Raslan, WM Ezzat, MF Abdel Hamid… - … Health Journal, 15 (3) …, 2009 - apps.who.int
We assessed the dermatological manifestations associated with chronic hepatitis C virus [‎
HCV]‎ infection and their association with liver status. Of 155 patients with chronic HCV …

Hepatitis C virus serologic relapse after treatment with direct-acting antivirals is dependent on viral RNA levels in peripheral blood mononuclear cells and the grade of …

MDA Abd Alla, MK El Awady, RM Dawood… - Archives of …, 2018 - Springer
The disappearance of hepatitis C virus (HCV) from serum and tissues for 12 weeks after the
end of treatment (EOT) with direct-acting antivirals (DAAs) is known as a “sustained virologic …

Impact of OAS1 Exon 7 rs10774671 Genetic Variation on Liver Fibrosis Progression in Egyptian HCV Genotype 4 Patients

NG Bader El Din, MA Anany, RM Dawood… - Viral …, 2015 - liebertpub.com
The aim of this study was to assess the impact of genetic variants of oligoadenylate
synthetase 1 (OAS1) single-nucleotide polymorphism (SNP) rs10774671 at the exon 7 …

Design, synthesis, and biological evaluation of new 4-thiazolidinone derivatives substituted with benzimidazole ring as potential chemotherapeutic agents

GN Masoud, AM Youssef, MM Abdel Khalek… - Medicinal Chemistry …, 2013 - Springer
In search of novel antiviral and anticancer agents with promising pharmacotoxicological
profile, a study was initiated to synthesize new 2-thioxo-4-thiazolidinones as well as 2 …