Chromosomes are the physical realization of genetic information and thus form the basis for
its readout and propagation. Here we present a high-resolution chromosomal contact map …

The chromodomain motif is found among certain chromosomal proteins of all eukaryotes.
The chromodomain fold–three beta strands packed against a C-terminal alpha helix …

Spindle assembly required during mitosis depends on microtubule polymerization. We
demonstrate that the evolutionarily conserved low-complexity protein, BuGZ, undergoes …

This mini-review is devoted to the problem genetic meaning of main polytene chromosome
structures–bands and interbands. Generally, densely packed chromatin forms black bands …

Dosage compensation in Drosophila is dependent on MSL proteins and involves
hypertranscription of the male X chromosome, which ensures equal X-linked gene …

The coordinated regulation of gene expression at the transcriptional level is fundamental to
development and homeostasis. Inducible systems are invaluable when studying …

Chromatin insulators are genetic elements implicated in the organization of chromatin and
the regulation of transcription. In Drosophila, different insulator types were characterized by …

Drosophila melanogaster polytene chromosomes display specific banding pattern; the
underlying genetic organization of this pattern has remained elusive for many years. In the …

The DNA in many organisms, including humans, is shown to be organized in topologically
associating domains (TADs). In Drosophila, several architectural proteins are enriched at …

Cells compartmentalize biochemical reactions using organelles, which can be membrane
enclosed or built entirely of proteins and ribonucleic acids. Recent studies indicate that …