Extracellular vesicles as nanotheranostic platforms for targeted neurological disorder interventions

HK Choi, M Chen, LL Goldston, KB Lee - Nano Convergence, 2024 - Springer
Abstract Central Nervous System (CNS) disorders represent a profound public health
challenge that affects millions of people around the world. Diseases such as Alzheimer's …

Multi-scale feature fusion for prediction of IDH1 mutations in glioma histopathological images

X Liu, W Hu, S Diao, DE Abera, D Racoceanu… - Computer Methods and …, 2024 - Elsevier
Background and objective Mutations in isocitrate dehydrogenase 1 (IDH1) play a crucial role
in the prognosis, diagnosis, and treatment of gliomas. However, current methods for …

Sequencing of cerebrospinal fluid cell-free DNA facilitated early differential diagnosis of intramedullary spinal cord tumors

R Chai, S An, H Lin, B Pang, H Yan, Y Liu, Y Wu… - NPJ Precision …, 2024 - nature.com
Pre-surgery differential diagnosis is valuable for personalized treatment planning in
intramedullary spinal cord tumors. This study assessed the performance of sequencing cell …

A brain metastasis liquid biopsy: Where are we now?

SD Robinson, J de Boisanger, FMG Pearl… - Neuro-Oncology …, 2024 - academic.oup.com
Brain metastases remain a challenging and feared complication for patients with cancer and
research in this area has lagged behind research into metastases to other organs. Due to …

Circulating Liquid Biopsy Biomarkers in Glioblastoma: Advances and Challenges

AA Seyhan - International Journal of Molecular Sciences, 2024 - mdpi.com
Gliomas, particularly glioblastoma (GBM), represent the most prevalent and aggressive
tumors of the central nervous system (CNS). Despite recent treatment advancements, patient …

A Concise Overview of Circulating Tumor DNA Detection for Solid Tumors

E Goold, E Raps, V McMurtry - Advances in …, 2024 - advancesinmolecularpathology.com
Molecular analysis is now an important component of almost any cancer diagnosis. Since
the advent of mutation-specific, targeted drugs, this testing has been achieved on tumor …