Conductive polymers: opportunities and challenges in biomedical applications

T Nezakati, A Seifalian, A Tan, AM Seifalian - Chemical reviews, 2018 - ACS Publications
Research pertaining to conductive polymers has gained significant traction in recent years,
and their applications range from optoelectronics to material science. For all intents and …

Intrinsic mechanisms of neuronal axon regeneration

M Mahar, V Cavalli - Nature Reviews Neuroscience, 2018 - nature.com
Permanent disabilities following CNS injuries result from the failure of injured axons to
regenerate and rebuild functional connections with their original targets. By contrast, injury …

Therapeutic repair for spinal cord injury: combinatory approaches to address a multifaceted problem

JM Griffin, F Bradke - EMBO molecular medicine, 2020 - embopress.org
The recent years saw the advent of promising preclinical strategies that combat the
devastating effects of a spinal cord injury (SCI) that are progressing towards clinical trials …

[HTML][HTML] Electrical stimulation to enhance axon regeneration after peripheral nerve injuries in animal models and humans

T Gordon - Neurotherapeutics, 2016 - Elsevier
Injured peripheral nerves regenerate their lost axons but functional recovery in humans is
frequently disappointing. This is so particularly when injuries require regeneration over long …

Electrical stimulation to enhance peripheral nerve regeneration: Update in molecular investigations and clinical translation

KJ Zuo, T Gordon, KM Chan, GH Borschel - Experimental neurology, 2020 - Elsevier
Peripheral nerve injuries are common and frequently result in incomplete functional
recovery even with optimal surgical treatment. Permanent motor and sensory deficits are …

Electrical stimulation for the treatment of spinal cord injuries: A review of the cellular and molecular mechanisms that drive functional improvements

RM Dorrian, CF Berryman, A Lauto… - Frontiers in Cellular …, 2023 - frontiersin.org
Spinal cord injury (SCI) is a devastating condition that causes severe loss of motor, sensory
and autonomic functions. Additionally, many individuals experience chronic neuropathic …

Strategies to promote peripheral nerve regeneration: electrical stimulation and/or exercise

T Gordon, AW English - European Journal of Neuroscience, 2016 - Wiley Online Library
Enhancing the regeneration of axons is often considered to be a therapeutic target for
improving functional recovery after peripheral nerve injury. In this review, the evidence for …

Contact separation triboelectric nanogenerator based neural interfacing for effective sciatic nerve restoration

M Zhou, M Huang, H Zhong, C Xing… - Advanced Functional …, 2022 - Wiley Online Library
Peripheral nerve injuries represent one of the most common causes of permanent
disabilities. Therapeutic electrical stimulation has been widely used in neural regeneration …

Neuronal intrinsic mechanisms of axon regeneration

K Liu, A Tedeschi, KK Park, Z He - Annual review of …, 2011 - annualreviews.org
Failure of axon regeneration after central nervous system (CNS) injuries results in
permanent functional deficits. Numerous studies in the past suggested that blocking …

Electrical stimulation to promote peripheral nerve regeneration

MP Willand, MA Nguyen… - … and neural repair, 2016 - journals.sagepub.com
Peripheral nerve injury afflicts individuals from all walks of life. Despite the peripheral
nervous system's intrinsic ability to regenerate, many patients experience incomplete …