HPV induced R-loop formation represses innate immune gene expression while activating DNA damage repair pathways

CW Templeton, LA Laimins - PLoS pathogens, 2024 - journals.plos.org
R-loops are trimeric nucleic acid structures that form when an RNA molecule hybridizes with
its complementary DNA strand, displacing the opposite strand. These structures regulate …

[HTML][HTML] LC3B: A microtubule-associated protein influences disease progression and prognosis

Y Chen, H Yi, S Liao, J He, Y Zhou, Y Lei - Cytokine & Growth Factor …, 2024 - Elsevier
Microtubule-associated protein 1 light chain 3B (MAP1LC3B, also known as LC3B) is a
mammalian homolog of the autophagy-related protein 8 (ATG8) family. It plays a crucial role …

To eat or not to eat: a critical review on the role of autophagy in prostate carcinogenesis and prostate cancer therapeutics

NJ Kurganovs, N Engedal - Frontiers in Pharmacology, 2024 - frontiersin.org
Around 1 in 7 men will be diagnosed with prostate cancer during their lifetime. Many strides
have been made in the understanding and treatment of this malignancy over the years …