Cancer and stem cells appear to share a common metabolic profile that is characterized by
high utilization of glucose through aerobic glycolysis. In the presence of sufficient nutrients …

Most, if not all mitochondrial functions, including adenosine-5′-triphosphate (ATP)
production and regulation of apoptosis and Ca 2+ homeostasis, are inextricably linked to …

The conversion of neural stem cells into neurons is associated with the remodeling of
organelles, but whether and how this is causally linked to fate change is poorly understood …

Triple‐negative breast cancer (TNBC) is a subgroup of 15%‐20% of diagnosed breast
cancer patients. It is generally considered to be the most difficult breast cancer subtype to …

Mitochondrial morphology is crucial for tissue homeostasis, but its role in cell differentiation
is unclear. We found that mitochondrial fusion was required for proper cardiomyocyte …

The non-invasive high-resolution spatial mapping of cell metabolism within tissues could
provide substantial advancements in assessing the efficacy of stem cell therapy and …

Mouse skin mesenchymal stem cells (msMSCs) are dermis CD105+ CD90+ CD73+ CD29+
CD34− mesodermal precursors which, after in vitro induction, undergo chondro, adipo, and …

FUS-proteinopathies, a group of heterogeneous disorders including ALS-FUS and FTLD-
FUS, are characterized by the formation of inclusion bodies containing the nuclear protein …

The structure of mitochondria is highly dynamic. Mitochondrial shape is cell-type specific
and can be modified to meet changing requirements in energy production, calcium …

The dynamics, distribution and activity of subcellular organelles are integral to regulating
cell shape changes during various physiological processes such as epithelial cell formation …