Metabolic control by heat stress determining cell fate to ferroptosis for effective cancer therapy

S Xie, W Sun, C Zhang, B Dong, J Yang, M Hou… - ACS …, 2021 - ACS Publications
Flexible manipulation of the fate of cancer cells through exogenous stimulation-induced
metabolic reprogramming could handle the cellular plasticity-derived therapies resistance …

[HTML][HTML] Creatine-mediated crosstalk between adipocytes and cancer cells regulates obesity-driven breast cancer

OA Maguire, SE Ackerman, SK Szwed, AV Maganti… - Cell metabolism, 2021 - cell.com
Obesity is a major risk factor for adverse outcomes in breast cancer; however, the underlying
molecular mechanisms have not been elucidated. To investigate the role of crosstalk …

Transcriptome analysis of the growth performance of hybrid mandarin fish after food conversion

WZ Guan, GF Qiu - PloS One, 2020 - journals.plos.org
During recent years, China has become a hotspot for the domestication of mandarin fish,
and this is of great commercial value. Although the food preference of domesticated …

Behavioral impairments and disrupted mitochondrial energy metabolism induced by polypropylene microplastics in zebrafish larvae

J Hua, T Zhang, X Chen, B Zhu, M Zhao, K Fu… - Science of The Total …, 2024 - Elsevier
Polypropylene microplastics (PP-MPs) are emerging pollutant commonly detected in various
environmental matrices and organisms, while their adverse effects and mechanisms are not …

Assessing the bioavailability and biotoxicity of spiromesifen and its main metabolite spiromesifen-enol (M01) reveals the defense mechanisms of earthworms (Eisenia …

J Fang, B Wang, K Fang, T Liu, S Yan… - Science of The Total …, 2022 - Elsevier
As a promising acaricide and potentially hazardous material, the defense mechanisms of
non-target organisms to its exposure are unknown. This study investigates the bioavailability …

The acyl-CoA synthetase TgACS1 allows neutral lipid metabolism and extracellular motility in Toxoplasma gondii through relocation via its peroxisomal targeting …

S Charital, S Shunmugam, S Dass, AM Alazzi… - Mbio, 2024 - Am Soc Microbiol
Apicomplexa parasites cause major diseases such as toxoplasmosis and malaria that have
major health and economic burdens. These unicellular pathogens are obligate intracellular …

[HTML][HTML] Toxoplasma acyl-CoA synthetase TgACS3 is crucial to channel host fatty acids in lipid droplets and for parasite propagation

S Dass, S Shunmugam, S Charital, S Duley… - Journal of Lipid …, 2024 - Elsevier
Apicomplexa comprise important pathogenic parasitic protists that heavily depend on lipid
acquisition to survive within their human host cells. Lipid synthesis relies on the …

Characterization of the Bubblegum acyl-CoA synthetase of Microchloropsis gaditana

E Billey, L Magneschi, S Leterme… - Plant …, 2021 - academic.oup.com
The metabolic pathways of glycerolipids are well described in cells containing chloroplasts
limited by a two-membrane envelope but not in cells containing plastids limited by four …

Transcriptomic profiling reveals potential regulatory genes and molecular mechanisms of residual feed intake in Jian carp (Cyprinus carpio var. Jian)

W Wang, Y Xu, Z Zhang, K Jiang, J Li, W Feng… - Aquaculture, 2024 - Elsevier
Feed efficiency is one of the most important economic traits in animal production. Improving
feed efficiency through genetic selection or other approaches will reduce production costs …

Functional Characterization of Long-Chain Acyl-CoA Synthetase Gene Family from the Oleaginous Alga Chromochloris zofingiensis

T Wu, Y Fu, Y Shi, Y Li, Y Kou, X Mao… - Journal of agricultural …, 2020 - ACS Publications
Long-chain acyl-coenzyme A (CoA) synthetase (LACS) catalyzes the formation of acyl-CoAs
from free fatty acids, which is pivotal for lipid metabolism. Here, we confirmed the presence …