The bacterial chromosome must be compacted more than 1,000-fold to fit into the
compartment in which it resides. How it is condensed, organized and ultimately segregated …

The separation and segregation of newly replicated bacterial chromosomes can be
constrained by the formation of circular chromosome dimers caused by crossing over during …

Mobile genetic elements (MGEs) sequester and mobilize antibiotic resistance genes across
bacterial genomes. Efficient and reliable identification of such elements is necessary to …

The Microviridae comprises icosahedral lytic viruses with circular single-stranded DNA
genomes. The family is divided into two distinct groups based on genome characteristics …

It is often assumed that eukarya originated from archaea. This view has been recently
supported by phylogenetic analyses in which eukarya are nested within archaea. Here, I …

Growth and proliferation of all cell types require intricate regulation and coordination of
chromosome replication, genome segregation, cell division and the systems that determine …

Prokaryotic genomes are replete with mobile genetic elements (MGE) that span a continuum
of replication autonomy. On numerous occasions during microbial evolution, diverse MGE …

Bacteriophages co-exist and co-evolve with their hosts in natural environments. Virulent
phages lyse infected cells through lytic cycles, whereas temperate phages often remain …

Summary It was Barbara McClintock who first described the problems of segregation arising
from the circularity of chromosomes during her studies on maize variegation (1). The …

The 2 465 177 bp genome of Sulfolobus islandicus LAL14/1, host of the model rudivirus
SIRV2, was sequenced. Exhaustive comparative genomic analysis of S. islandicus LAL14/1 …