BACKGROUND: Pregnancy complicated by cancer is relatively rare but, as women in
western societies tend to delay childbearing to the third and fourth decade of life, this …

The success of tyrosine kinase inhibitors (TKIs) in the treatment of chronic myeloid
leukaemia (CML) has resulted in a return to a normal life expectancy for the majority of …

Prolonged survival in patients with chronic myeloid leukemia treated with BCR‐ABL1‐
targeted tyrosine kinase inhibitors allows consideration of parenthood for patients on chronic …

Leukemia in pregnancy remains a challenging therapeutic prospect. The prevalence is low
at∼ 1 in 10 000 pregnancies, and as a result data are limited to small retrospective series …

The management of patients with chronic myeloid leukemia (CML) during pregnancy has
become recently a matter of continuous debate. The introduction of the Tyrosine Kinase …

The last decade has witnessed important advances in the field of managing cancer during
pregnancy. However, still limited data is available on the safety of administering targeted …

Lutein cells produce progestins that support pregnancy. Steroidogenesis requires
coordination of the anabolic and catabolic pathways of lipid metabolism. Peroxisome …

The NCCN Guidelines for Chronic Myeloid Leukemia (CML) provide recommendations for
the management of chronic-phase and advanced-phase CML in adult patients. The median …

Introduction: Since the introduction of tyrosine kinase inhibitors (TKIs) therapy, chronic
myeloid leukemia (CML), has moved from a fatal illness to a manageable disease with a …

Chronic myelogenous leukemia (CML) is usually diagnosed in the chronic phase. Untreated
chronic phase CML will eventually progress to advanced phase (accelerated or blast phase) …