Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles

AP Singh, A Biswas, A Shukla, P Maiti - Signal transduction and …, 2019 - nature.com
The application of nanomedicines is increasing rapidly with the promise of targeted and
efficient drug delivery. Nanomedicines address the shortcomings of conventional therapy, as …

Neuroprotective mechanisms of resveratrol in Alzheimer's disease: role of SIRT1

BAQ Gomes, JPB Silva, CFR Romeiro… - Oxidative medicine …, 2018 - Wiley Online Library
Alzheimer's disease (AD) is a progressive and neurodegenerative disorder of the cortex and
hippocampus, which eventually leads to cognitive impairment. Although the etiology of AD …

Molecular mechanisms of neuroinflammation in aging and Alzheimer's disease progression

FL Andronie-Cioara, AI Ardelean… - International journal of …, 2023 - mdpi.com
Aging is the most prominent risk factor for late-onset Alzheimer's disease. Aging associates
with a chronic inflammatory state both in the periphery and in the central nervous system, the …

Anti-inflammatory effects of resveratrol: Mechanistic insights

D de Sá Coutinho, MT Pacheco, RL Frozza… - International journal of …, 2018 - mdpi.com
Inflammation is the principal response invoked by the body to address injuries. Despite
inflammation constituting a crucial component of tissue repair, it is well known that …

Drug delivery systems, CNS protection, and the blood brain barrier

RK Upadhyay - BioMed research international, 2014 - Wiley Online Library
Present review highlights various drug delivery systems used for delivery of pharmaceutical
agents mainly antibiotics, antineoplastic agents, neuropeptides, and other therapeutic …

[HTML][HTML] Neuroprotective action of resveratrol

S Bastianetto, C Ménard, R Quirion - Biochimica et Biophysica Acta (BBA) …, 2015 - Elsevier
Low-to-moderate red wine consumption appeared to reduce age-related neurological
disorders including macular degeneration, stroke, and cognitive deficits with or without …

Natural antioxidant compounds as potential pharmaceutical tools against neurodegenerative diseases

A Marino, M Battaglini, N Moles, G Ciofani - ACS omega, 2022 - ACS Publications
Natural antioxidants are a very large diversified family of molecules classified by activity
(enzymatic or nonenzymatic), chemical-physical properties (eg, hydrophilic or lipophilic) …

Role of phenolic acid, tannins, stilbenes, lignans and flavonoids in human health–a review

O Oluwole, WB Fernando, J Lumanlan… - … Journal of Food …, 2022 - Wiley Online Library
Phytonutrients such as phenolics play important roles in health and well‐being. The main
phenolic compounds include phenolic acid, tannins, stilbenes, lignans and flavonoids …

The interaction of polyphenols and the gut microbiota in neurodegenerative diseases

Y Zhang, W Yu, L Zhang, M Wang, W Chang - Nutrients, 2022 - mdpi.com
Polyphenols are secondary metabolites of plants and play a potential role in the prevention
and treatment of neurodegenerative diseases (NND) such as Alzheimer's disease (AD) and …

Polyphenol stilbenes: molecular mechanisms of defence against oxidative stress and aging‐related diseases

M Reinisalo, A Kårlund, A Koskela… - Oxidative medicine …, 2015 - Wiley Online Library
Numerous studies have highlighted the key roles of oxidative stress and inflammation in
aging‐related diseases such as obesity, type 2 diabetes, age‐related macular degeneration …