Minerals and trace elements are micronutrients that are essential to the human body but
present only in traceable amounts. Nonetheless, they exhibit well-defined biochemical …

The maintenance of iron homeostasis is essential for proper endocrine function. A growing
body of evidence suggests that iron imbalance is a key factor in the development of several …

High iron is a risk factor for type 2 diabetes mellitus (T2DM) and affects most of its cardinal
features: decreased insulin secretion, insulin resistance, and increased hepatic …

A bidirectional relationship exists between adipose tissue metabolism and iron regulation.
Total body fat, fat distribution and exercise influence iron status and components of the iron …

Hyperferritinaemia is a common laboratory finding that is often associated with metabolic
dysfunction and fatty liver. Metabolic hyperferritinaemia reflects alterations in iron …

Aims PCSK9 loss of function genetic variants are associated with lower low-density
lipoprotein cholesterol but also with higher plasma glucose levels and increased risk of Type …

We have previously demonstrated that iron overload in hepatic reticuloendothelial system
cells (RES) is associated with severe nonalcoholic steatohepatitis (NASH) and advanced …

OBJECTIVE The bidirectional relationship between iron metabolism and glucose
homeostasis is increasingly recognized. Several pathways of iron metabolism are modified …

Iron can affect the clinical course of several chronic metabolic diseases such as type 2
diabetes, obesity, non-alcoholic fatty liver disease, and atherosclerosis. Iron overload can …

Pathogen virulence exists on a continuum. The strategies that drive symptomatic or
asymptomatic infections remain largely unknown. We took advantage of the concept of lethal …