New insights into the pathogenesis and nonsurgical management of Graves orbitopathy
Graves orbitopathy, also known as thyroid eye disease or thyroid-associated orbitopathy, is
visually disabling, cosmetically disfiguring and has a substantial negative impact on a …
visually disabling, cosmetically disfiguring and has a substantial negative impact on a …
Graves' disease
TJ Smith, L Hegedüs - New England Journal of Medicine, 2016 - Mass Medical Soc
Graves’ Disease | New England Journal of Medicine Skip to main content The New England
Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …
Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …
Teprotumumab for thyroid-associated ophthalmopathy
TJ Smith, GJ Kahaly, DG Ezra… - … England Journal of …, 2017 - Mass Medical Soc
Background Thyroid-associated ophthalmopathy, a condition commonly associated with
Graves' disease, remains inadequately treated. Current medical therapies, which primarily …
Graves' disease, remains inadequately treated. Current medical therapies, which primarily …
Teprotumumab for the treatment of chronic thyroid eye disease
S Ugradar, J Kang, AL Kossler, E Zimmerman, J Braun… - Eye, 2022 - nature.com
Background Teprotumumab, a novel IGF-1R antibody was recently shown to significantly
reduce the signs of active Thyroid eye disease (TED). The current study reviews its efficacy …
reduce the signs of active Thyroid eye disease (TED). The current study reviews its efficacy …
Insulin-like growth factor-I receptor and thyroid-associated ophthalmopathy
TJ Smith, JA Janssen - Endocrine Reviews, 2019 - academic.oup.com
Thyroid-associated ophthalmopathy (TAO) is a complex disease process presumed to
emerge from autoimmunity occurring in the thyroid gland, most frequently in Graves disease …
emerge from autoimmunity occurring in the thyroid gland, most frequently in Graves disease …
Fibrocytes: emerging effector cells in chronic inflammation
Fibrocytes are mesenchymal cells that arise from monocyte precursors. They are present in
injured organs and have both the inflammatory features of macrophages and the tissue …
injured organs and have both the inflammatory features of macrophages and the tissue …
Current insights into the pathogenesis of Graves' ophthalmopathy
RS Bahn - Hormone and Metabolic Research, 2015 - thieme-connect.com
Environmental, genetic, and immune factors are at play in the development of the variable
clinical manifestations of Graves' ophthalmopathy (GO). Among the environmental …
clinical manifestations of Graves' ophthalmopathy (GO). Among the environmental …
Graves' disease
TF Davies, S Andersen, R Latif, Y Nagayama… - Nature reviews Disease …, 2020 - nature.com
Graves' disease (GD) is an autoimmune disease that primarily affects the thyroid gland. It is
the most common cause of hyperthyroidism and occurs at all ages but especially in women …
the most common cause of hyperthyroidism and occurs at all ages but especially in women …
Current concepts in the molecular pathogenesis of thyroid-associated ophthalmopathy
Y Wang, TJ Smith - Investigative ophthalmology & visual …, 2014 - iovs.arvojournals.org
Graves' disease (GD) is a common autoimmune condition. At its core, stimulatory
autoantibodies are directed at the thyroid-stimulating hormone receptor (TSHR), resulting in …
autoantibodies are directed at the thyroid-stimulating hormone receptor (TSHR), resulting in …
CD34+ stromal cells/fibroblasts/fibrocytes/telocytes as a tissue reserve and a principal source of mesenchymal cells. Location, morphology, function and role in …
L Díaz-Flores, R Gutiérrez, MP García… - Histology and …, 2014 - europepmc.org
We review the morphofunctional characteristics of CD34+ stromal fibroblastic/fibrocytic cells
(CD34+ SFCs) and report our observations. We consider the following aspects of CD34+ …
(CD34+ SFCs) and report our observations. We consider the following aspects of CD34+ …