Background Despite substantial decreases in recent decades, acute gastroenteritis causes
the second greatest burden of all infectious diseases worldwide. Noroviruses are a leading …

Norovirus, an RNA virus of the family Caliciviridae, is a human enteric pathogen that causes
substantial morbidity across both health care and community settings. Several factors …

Estimates of foodborne illness can be used to direct food safety policy and interventions. We
used data from active and passive surveillance and other sources to estimate that each year …

Estimation of pathogen-specific causes of child diarrhea deaths is needed to guide vaccine
development and other prevention strategies. We did a systematic review of articles …

The cell tropism of human noroviruses and the development of an in vitro infection model
remain elusive. Although susceptibility to individual human norovirus strains correlates with …

Although recognized as the leading cause of epidemic acute gastroenteritis across all age
groups, norovirus has remained poorly characterized with respect to its endemic disease …

The ancient biological'arms race'between microbial pathogens and humans has shaped
genetic variation in modern populations, and this has important implications for the growing …

Background Cases of rotavirus-associated acute gastroenteritis have declined since the
introduction of rotavirus vaccines, but the burden of norovirus-associated acute …

Noroviruses are now recognized as the leading cause of epidemics of gastroenteritis and an
important cause of sporadic gastroenteritis among both children and adults. In the United …

Noroviruses are major pathogens associated with acute gastroenteritis worldwide. Their
RNA genomes are diverse, with two major genogroups (GI and GII) comprised of at least 28 …