Ferroptosis therapy induced by iron‐catalyzed Fenton reaction has offered enormous
opportunities for tumor therapy. Unfortunately, high catalytic activity ferrous (Fe2+)‐based …

Small heterodimer partner-interacting leucine zipper (SMILE) is a member of the CREB/ATF
family of basic leucine zipper (bZIP) transcription factors. SMILE has two isoforms, a small …

Immune checkpoint inhibitors currently serve an important role in prolonging patients' overall
survival. However, the prognostic signatures of immune checkpoint inhibitors in colorectal …

Thalassemia is a disease of erythrocytes that varies largely on its genetic composition and
associated clinical presentation. Though some patients may remain asymptomatic, those …

Background: Beta thalassemia major (Cooley's anemia) is a congenital genetic blood
disorder resulting from a deficiency of β-globin chains due to severe anemia that depends …

Thalassemia represents a diverse group of inherited hematological disorders characterized
by defective globin chain synthesis, leading to chronic anemia and associated …

Thalassemia is one of the most common inherited disorders of erythrocytes, caused by
abnormalities in the production of globin chains. The clinical spectrum of thalassemia is …

Background: Thalassemia is a genetic blood disorder characterized by abnormal
hemoglobin production. MicroRNAs (miRNAs) regulate gene expression and are implicated …

Diabetes is a diverse metabolic disease that is caused by increased levels of blood glucose,
which also leads to the generation of several other complications. The formation of wounds …

Background: Emerging evidence has recognized that anemia and iron deficiency are
recurrent comorbidities in chronic heart failure (HF) and several trials have established that …