We discuss the fascinating pharmacology of formylpeptide receptor 2 (FPR2; often referred
to as FPR2/ALX since it binds lipoxin A4). Initially identified as a low‐affinity 'relative'of …

In the working-age population worldwide, diabetic retinopathy (DR), a prevalent
complication of diabetes, is the main cause of vision impairment. Chronic low-grade …

Both the initiation and the resolution of inflammatory responses are governed by the
sequential activation, migration, and control/suppression of immune cells at the site of injury …

Stimulation of retinal photoreceptors with elevated glucose concentration (30 mM) for 96 h,
served as diabetic retinopathy in vitro model to study Resolvin D1 (50 nM) effects on …

In the last twenty years an impressive body of evidence in diverse inflammatory animal
disease models and human tissues, has established polyunsaturated fatty acids (PUFA) …

Mucin secretion from conjunctival goblet cells forms the tear film mucin layer and requires
regulation to function properly. Maresin 1 (MaR1) is a specialized proresolving mediator …

Purpose The etiology of meibomian gland dysfunction (MGD) is incompletely understood,
despite being a common ophthalmic condition and an area of unmet medical need. It is …

Meibomian gland dysfunction (MGD) is a leading cause of dry eye disease and one of the
most common ophthalmic conditions encountered in eye clinics worldwide. These holocrine …

Under physiologic conditions, conjunctival goblet cells (CGCs) secrete mucins into the tear
film to preserve ocular surface homeostasis. Specialized proresolving mediators (SPMs) …

Leukotriene B4 (LTB4) is a major proinflammatory mediator important in host defense,
whereas resolvins (Rvs) are produced during the resolution phase of inflammation. The …