Reactive oxygen species (ROS) are by‐products of normal cell activity. They are produced
in many cellular compartments and play a major role in signaling pathways. Overproduction …

Colorectal cancer (CRC) is the third most common cancer worldwide and the leading cause
of cancer-related deaths. Recently, several studies have demonstrated that gut microbiota …

Surrogate end-point biomarkers (SEBs) have become widely used in short-term cancer
chemoprevention trials in place of cancer end points. This paper discusses criteria relevant …

An early response to an acute inflammatory insult, such as wound healing or experimental
glomerulonephritis, is the conversion of arginine to the cytostatic molecule nitric oxide (NO) …

Previous in vitro and in vivo studies have suggested that lactobacilli can exert
antiproliferative effects on the gastrointestinal epithelium. However, their role in affecting the …

Background. Functional probiotics may prevent Helicobacter pylori infection, and some
evidence suggests that they also possess antitumor properties. Lactobacillus brevis (CD2) is …

Gastric cancer is still the second leading cause of cancer death worldwide, accounting for
about 10% of newly diagnosed neoplasms. In the last decades, an emerging role has been …

Previous in vivo studies have suggested that lactobacilli can exert anti-proliferative effects
on the gastric epithelium. However, few data are available on their mechanisms of action …

Colorectal cancers are a significant cause of mortality in Western societies. The progression
of the disease from normal epithelium to the acquisition of the malignant phenotype is …

Epidemiological and experimental studies suggest a protective role of estrogens against
colorectal cancer. This effect seems to be mediated by their binding to estrogen receptor …