Library construction for next-generation sequencing: overviews and challenges

SR Head, HK Komori, SA LaMere, T Whisenant… - …, 2014 - Taylor & Francis
High-throughput sequencing, also known as next-generation sequencing (NGS), has
revolutionized genomic research. In recent years, NGS technology has steadily improved …

[HTML][HTML] The remodelling of actin composition as a hallmark of cancer

R Suresh, RJ Diaz - Translational Oncology, 2021 - Elsevier
Actin is a key structural protein that makes up the cytoskeleton of cells, and plays a role in
functions such as division, migration, and vesicle trafficking. It comprises six different cell …

A novel significance score for gene selection and ranking

Y Xiao, TH Hsiao, U Suresh, HIH Chen, X Wu… - …, 2014 - academic.oup.com
Motivation: When identifying differentially expressed (DE) genes from high-throughput gene
expression measurements, we would like to take both statistical significance (such as P …

IL-15 regulates homeostasis and terminal maturation of NKT cells

LE Gordy, JS Bezbradica, AI Flyak… - The Journal of …, 2011 - journals.aai.org
Semi-invariant NKT cells are thymus-derived innate-like lymphocytes that modulate
microbial and tumor immunity as well as autoimmune diseases. These immunoregulatory …

Systemic inflammation and survival of patients with prostate cancer: evidence from the Glasgow Inflammation Outcome Study

K Shafique, MJ Proctor, DC McMillan… - Prostate cancer and …, 2012 - nature.com
Background: There is some evidence that systemic inflammation may be associated with
survival in patients with prostate cancer; however, it is unclear whether this is independent of …

Bone marrow–derived cells contribute to the pathogenesis of pulmonary arterial hypertension

L Yan, X Chen, M Talati, BW Nunley… - American journal of …, 2016 - atsjournals.org
Rationale: Pulmonary arterial hypertension (PAH) is a progressive lung disease of the
pulmonary microvasculature. Studies suggest that bone marrow (BM)-derived circulating …

Validation of the neutrophil-to-lymphocyte ratio as a prognostic factor in a cohort of European prostate cancer patients

T Langsenlehner, EM Thurner, S Krenn-Pilko… - World journal of …, 2015 - Springer
Purpose Recent studies have expanded the concept that the systemic inflammatory
response has an important role in the progression of several solid tumors. The neutrophil-to …

[PDF][PDF] Type II transmembrane serine protease (TTSP) deregulation in cancer

SL Webb, AJ Sanders, MD Mason, WG Jiang - Front Biosci, 2011 - article.imrpress.com
[Frontiers in Bioscience 16, 539-552, January 1, 2011] 539 Type II Transmembrane Serine
Protease (TTSP) deregulation in cancer S Page 1 [Frontiers in Bioscience 16, 539-552 …

A study of diagnostic value of golgi protein GP73 and its genetic assay in primary hepatic carcinoma

Y Shi, J Chen, L Li, Z Sun, L Zen, S Xu… - … in cancer research …, 2011 - journals.sagepub.com
This study aimed to investigate the diagnostic values of GP73 protein in patients' serum with
primary hepatic carcinoma (PHC). Also GP73 mRNA expression level in peripheral blood …

High-altitude pulmonary hypertension in cattle (brisket disease): Candidate genes and gene expression profiling of peripheral blood mononuclear cells

JH Newman, TN Holt, LK Hedges… - Pulmonary …, 2011 - journals.sagepub.com
High-altitude pulmonary hypertension (HAPH) is a consequence of chronic alveolar
hypoxia, leading to hypoxic vasoconstriction and remodeling of the pulmonary circulation …