Cisplatin is a platinum-based chemotherapeutic that has long since been effective against a
variety of solid-cancers, substantially improving the five-year survival rates for cancer …

Objective Evaluation of traditionally used royal jelly (RJ) for the management of hepato-renal
damage and gastrointestinal ulcerations caused by diclofenac. Methods Forty adult male …

Background: Cyclophosphamide (CP) causes premature ovarian failure (POF) due to
ovarian toxicity. The toxicity mechanism is attributed to oxidative stress, inflammation, and …

Aim In the present investigation, we compared the effects of mesenchymal stem cells
extracted from bone marrow (BMSCs) and crab chitosan nanoparticles (CCNPs) on renal …

Cisplatin is one of the most significant anticancer. However, its use is associated with
numerous toxicities especially nephrotoxicity. The main aim of this work was to examine the …

Background Despite cisplatin's long history as a cornerstone in cancer therapy, both
acquired chemoresistance and significant impacts on healthy tissues limit its use …

Background and purpose: The clinical use of the chemotherapeutic drug, doxorubicin
(DXR), is significantly limited by its extensive multi-organ toxicity. Dipeptidyl peptidase-4 …

Cisplatin (CP) is a powerful antineoplastic chemotherapeutic agent with broad-spectrum
properties. Acute and cumulative cardiotoxicity are major limiting factors for CP therapy …

Background and purpose: Kidney diseases impose significant global health challenges.
Potassium dichromate (PD) is a heavy metal frequently associated with nephrotoxicity. PD …

Background: Ursolic acid (UA) is a natural pentacyclic triterpenoid that is known for its
benefits under several pathological conditions. Cisplatin (CP) is among the most preferred …