Normothermic machine perfusion (NMP) aims to preserve organs ex vivo by simulating
physiological conditions such as body temperature. Recent advancements in NMP system …

The endogenous capacity of the kidney to repair is limited, and generation of new nephrons
after injury for adequate function recovery remains a need. Discovery of factors that promote …

Among strategies to limit ischemia/reperfusion (IR) injuries in transplantation, cell therapy
using stem cells to condition/repair transplanted organs appears promising. We …

The increasing number of patients on the kidney transplant waiting list underlines the need
to expand the donor pool and improve kidney graft utilization. By protecting kidney grafts …

The use of high-risk renal grafts for transplantation requires the optimization of pretransplant
assessment and preservation reconditioning strategies to decrease the organ discard rate …

Background Personalized disease models are crucial for assessing the specific response of
diseased cells to drugs, particularly novel biological therapeutics. Extracellular vesicles …

Normothermic machine perfusion (NMP) of human kidneys is a new preservation technique
that allows for the assessment and treatment of kidneys prior to transplantation. However …

ABO blood group antigens present an immunological barrier in transplantation, restricting
organ donor-recipient matches to blood group compatible pairings only. Due to the chronic …

Pagina 1 van 14 Inaugural Lecture for Obtaining Professor Title in Translational Pediatric
Nephrology in the University of Amste Page 1 Pagina 1 van 14 Inaugural Lecture for Obtaining …

Эндогенная способность почек к репарации ограничена, и генерация новых нефронов
после повреждения для адекватного восстановления функций остается …