[HTML][HTML] Progress in biomaterials inspired by the extracellular matrix

Z Chen, C Du, S Liu, J Liu, Y Yang, L Dong, W Zhao… - Giant, 2024 - Elsevier
Inspired by the extracellular matrix (ECM), biomaterials have emerged as promising
strategies in the biomedical research and engineering domain, offering unique …

Advances in photocrosslinked natural hydrogel‐based microspheres for bone repair

HR Li, J Zhou, YW Zhou, JW Dao… - Journal of Polymer …, 2024 - Wiley Online Library
In recent years, the prevalence of bone diseases is showing an increasing trend, which is
mainly attributed to the aging of the global population. However, bone repair and …

Stem cell recruitment polypeptide hydrogel microcarriers with exosome delivery for osteoarthritis treatment

L Yang, W Li, Y Zhao, Y Wang, L Shang - Journal of Nanobiotechnology, 2024 - Springer
With the accelerated aging tendency, osteoarthritis (OA) has become an intractable global
public health challenge. Stem cells and their derivative exosome (Exo) have shown great …

[HTML][HTML] Microenvironment-responsive metal-phenolic network release platform with ROS scavenging, anti-pyroptosis, and ECM regeneration for intervertebral disc …

H Zhou, J He, R Liu, J Cheng, Y Yuan, W Mao, J Zhou… - Bioactive Materials, 2024 - Elsevier
Intervertebral disc degeneration (IVDD) can be caused by aging, injury, and genetic factors.
The pathological changes associated with IVDD include the excessive accumulation of …

Transforming Osteoarthritis Treatment: Embracing Hydrogel Microspheres

J Chen, X Zhou, Y Li, T Liu, W Ding, F He… - ACS Materials …, 2024 - ACS Publications
Osteoarthritis (OA) is a chronic condition characterized by degeneration of the articular
cartilage and subsequent bone hyperplasia. With the increasing prevalence driven by …

Hydrogel microspheres for stem cell recruitment and induction of directed differentiation in osteoarthritis therapy

H Yu, H Luo, J Chen, X Hu, Y Chen, J Zhong… - Chemical Engineering …, 2024 - Elsevier
The utilization of stem cell biotechnology for osteoarthritis (OA) treatment is hindered by high
operational costs, difficulties in maintaining stem cell viability, and limited efficacy of …

[HTML][HTML] Designing polysaccharide materials for tissue repair and regeneration

A Jin, Y Shao, F Wang, J Feng, L Lei, M Dai - APL Materials, 2024 - pubs.aip.org
Tissue repair and regeneration are critical processes for maintaining the integrity and
function of various organs and tissues. Recently, polysaccharide materials and protein …

A novel metal‐organic framework encapsulated iridium oxide nanozyme enhanced antisense oligonucleotide combo for osteoarthritis synergistic therapy

S Wu, F Nan, K Zhang, W Hao, D Shi, Y Li, W Deng… - …, 2024 - Wiley Online Library
Osteoarthritis (OA) is associated with metabolic imbalance of articular cartilage and an
increase of intracellular reactive oxygen species (ROS). Synergistic therapy based on the …

Precise Cell Type Electrical Stimulation Therapy Via Force‐electric Hydrogel Microspheres for Cartilage Healing

Z Han, F Wang, W Xiong, C Meng, Y Yao… - Advanced …, 2024 - Wiley Online Library
Electrical stimulation enhances cellular activity, promoting tissue regeneration and repair.
However, specific cells and maintaining a stable energy supply are challenges for precise …

Nanocomposite Hydrogels: A Promising Approach for the Treatment of Degenerative Joint Diseases

Q Chen, Z Zheng, M Lin, Z Guo, H Huang, Q Xue… - Small …, 2024 - Wiley Online Library
Degenerative joint diseases, as a global public health issue, impose significant burdens on
patients' lives and substantial economic costs on society. Currently, the primary modalities …