PI3K/AKT signaling pathway as a critical regulator of Cisplatin response in tumor cells

ZN Navaei, G Khalili-Tanha, AS Zangouei… - Oncology …, 2022 - pmc.ncbi.nlm.nih.gov
Chemotherapy is one of the main therapeutic modalities for cancer patients. Cisplatin
(CDDP), as one of the first-line drugs, is of great importance in the chemotherapy of various …

Long non-coding RNAs as the critical regulators of PI3K/AKT, TGF-β, and MAPK signaling pathways during breast tumor progression

A Maharati, M Moghbeli - Journal of translational medicine, 2023 - Springer
Breast cancer (BC) as one of the most common causes of human deaths among women, is
always considered one of the global health challenges. Despite various advances in …

Long non-coding RNAs as the critical regulators of epithelial mesenchymal transition in colorectal tumor cells: an overview

AA Hamidi, G Khalili-Tanha, Z Nasrpour Navaei… - Cancer cell …, 2022 - Springer
Colorectal cancer (CRC) is the second most common cause of cancer mortality and a major
health challenge worldwide. Despite advances in therapeutic and diagnostic methods, there …

Long non-coding RNAs as the critical regulators of doxorubicin resistance in tumor cells

G Khalili-Tanha, M Moghbeli - Cellular & Molecular Biology Letters, 2021 - Springer
Resistance against conventional chemotherapeutic agents is one of the main reasons for
tumor relapse and poor clinical outcomes in cancer patients. Various mechanisms are …

[HTML][HTML] Cell cycle related long non-coding RNAs as the critical regulators of breast cancer progression and metastasis

AS Zangouei, M Zangoue, N Taghehchian… - Biological …, 2023 - SciELO Chile
Cell cycle is one of the main cellular mechanisms involved in tumor progression. Almost all
of the active molecular pathways in tumor cells directly or indirectly target the cell cycle …

Molecular mechanisms of the microRNA-132 during tumor progressions

M Moghbeli, AS Zangouei, Z Nasrpour Navaii… - Cancer Cell …, 2021 - Springer
Cancer as one of the leading causes of human deaths has always been one of the main
health challenges in the world. Despite recent advances in therapeutic and diagnostic …

Molecular interactions of miR-338 during tumor progression and metastasis

M Moghbeli - Cellular & molecular biology letters, 2021 - Springer
Background Cancer, as one of the main causes of human deaths, is currently a significant
global health challenge. Since the majority of cancer-related deaths are associated with late …

MicroRNAs as the pivotal regulators of cisplatin resistance in head and neck cancers

F Tolue Ghasaban, A Maharati, AS Zangouei… - Cancer cell …, 2023 - Springer
Although, there is a high rate of good prognosis in early stage head and neck tumors, about
half of these tumors are detected in advanced stages with poor prognosis. A combination of …

PRC2 mediated KLF2 down regulation: a therapeutic and diagnostic axis during tumor progression

N Taghehchian, A Maharati, I Akhlaghipour… - Cancer Cell …, 2023 - Springer
Surgery and chemo-radiotherapy are used as the common first-line treatment options in
many cancers. However, tumor relapse is observed in many cancer patients following such …

MicroRNAs as the critical regulators of autophagy-mediated cisplatin response in tumor cells

F Tolue Ghasaban, A Maharati, I Akhlaghipour… - Cancer Cell …, 2023 - Springer
Chemotherapy is one of the most common therapeutic methods in advanced and metastatic
tumors. Cisplatin (CDDP) is considered as one of the main first-line chemotherapy drugs in …