Neurophysiology in psychosis: The quest for disease biomarkers
Psychotic disorders affect 3% of the population at some stage in life, are a leading cause of
disability, and impose a great economic burden on society. Major breakthroughs in the …
disability, and impose a great economic burden on society. Major breakthroughs in the …
[HTML][HTML] The utility of twins in developmental cognitive neuroscience research: How twins strengthen the ABCD research design
The ABCD twin study will elucidate the genetic and environmental contributions to a wide
range of mental and physical health outcomes in children, including substance use, brain …
range of mental and physical health outcomes in children, including substance use, brain …
Association between P300 responses to auditory oddball stimuli and clinical outcomes in the psychosis risk syndrome
Importance In most patients, a prodromal period precedes the onset of schizophrenia.
Although clinical criteria for identifying the psychosis risk syndrome (PRS) show promising …
Although clinical criteria for identifying the psychosis risk syndrome (PRS) show promising …
Auditory and visual oddball stimulus processing deficits in schizophrenia and the psychosis risk syndrome: forecasting psychosis risk with P300
HK Hamilton, SW Woods, BJ Roach… - Schizophrenia …, 2019 - academic.oup.com
Identification of neurophysiological abnormalities associated with schizophrenia that
predate and predict psychosis onset may improve clinical prediction in the psychosis risk …
predate and predict psychosis onset may improve clinical prediction in the psychosis risk …
Endophenotype best practices
This review examines the current state of electrophysiological endophenotype research and
recommends best practices that are based on knowledge gleaned from the last decade of …
recommends best practices that are based on knowledge gleaned from the last decade of …
A polygenic risk score analysis of psychosis endophenotypes across brain functional, structural, and cognitive domains
S Ranlund, S Calafato, JH Thygesen… - American Journal of …, 2018 - Wiley Online Library
This large multi‐center study investigates the relationships between genetic risk for
schizophrenia and bipolar disorder, and multi‐modal endophenotypes for psychosis. The …
schizophrenia and bipolar disorder, and multi‐modal endophenotypes for psychosis. The …
Genetics in the ADHD clinic: how can genetic testing support the current clinical practice?
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder with a
childhood prevalence of 5%. In about two-thirds of the cases, ADHD symptoms persist into …
childhood prevalence of 5%. In about two-thirds of the cases, ADHD symptoms persist into …
Endophenotypes for alcohol use disorder: an update on the field
The endophenotype concept was first proposed as a strategy to use (purportedly)
genetically simpler phenotypes in gene identification studies for psychiatric disorders, and is …
genetically simpler phenotypes in gene identification studies for psychiatric disorders, and is …
Electrophysiological endophenotypes for schizophrenia
Endophenotypes are quantitative, heritable traits that may help to elucidate the
pathophysiologic mechanisms underlying complex disease syndromes, such as …
pathophysiologic mechanisms underlying complex disease syndromes, such as …
Brain-behavior relationships in externalizing: P3 amplitude reduction reflects deficient inhibitory control
GM Brennan, AR Baskin-Sommers - Behavioural Brain Research, 2018 - Elsevier
The use of endophenotypes to classify individuals at risk for or suffering from
psychopathology has been criticized for lacking specificity and predictive utility. This issue is …
psychopathology has been criticized for lacking specificity and predictive utility. This issue is …