Importance Smokers with chronic obstructive pulmonary disease (COPD) have particular
difficulty quitting. Long-term nicotine replacement therapy (LT-NRT) might offer a strategy for …

Objectives: To determine if time to initial antimicrobial is associated with progression of
severe sepsis to septic shock. Design: Retrospective cohort. Setting: Six hundred fifty-six …

Clinical decisions are crucial because they are related to human lives. Thus, managers and
decision makers in the clinical environment seek new solutions that can support their …

Importance Acute kidney injury (AKI) is a heterogeneous syndrome prevalent among
hospitalized patients. Personalized risk estimation and risk factor identification may allow …

Background Little is known about body weight status and the association between body
weight and common comorbidities in children and adults with Down syndrome (DS), autism …

Background Recent medical society opinions have questioned the use of early
antimicrobials in patients with sepsis, but without septic shock. Research Question Is time …

Background: Artificial intelligence–enabled electronic health record (EHR) analysis can
revolutionize medical practice from the diagnosis and prediction of complex diseases to …

Incidence of Acute Kidney Injury (AKI) has increased dramatically over the past two decades
due to rising prevalence of comorbidities and broadening repertoire of nephrotoxic …

Introduction This study evaluates racial and ethnic differences in urine drug screening and
patient consent to urine drug screening at a single tertiary care center. Methods We …

Transgender and gender non-conforming (TGNC) individuals face numerous barriers to
healthcare, which contribute to many health disparities. TGNC persons may choose gender …