What are the sensitivity and specificity of serologic tests for celiac disease? Do sensitivity and specificity vary in different populations?

ID Hill - Gastroenterology, 2005 - Elsevier
A number of serologic tests are available commercially for identifying individuals who
require an intestinal biopsy examination to diagnose celiac disease (CD). The aim of this …

The first large population based twin study of coeliac disease

L Greco, R Romino, I Coto, N Di Cosmo, S Percopo… - Gut, 2002 - gut.bmj.com
Background and aims: The genetic load in coeliac disease has hitherto been inferred from
case series or anecdotally referred twin pairs. We have evaluated the genetic component in …

The prevalence of coeliac disease in infertility

GF Meloni, S Dessole, N Vargiu, PA Tomasi… - Human …, 1999 - academic.oup.com
An increased incidence of reproductive problems, including infertility, miscarriage, low birth
weight newborns, and shorter duration of breast-feeding, are known to exist in women with …

IgA antibodies to tissue transglutaminase: an effective diagnostic test for celiac disease

R Troncone, F Maurano, M Rossi, M Micillo… - The Journal of …, 1999 - Elsevier
Objective: Tissue transglutaminase (tTG) is the main autoantigen recognized by endomysial
antibodies. The aim of this study was to assess sensitivity, specificity, and predictive value of …

Antibodies against synthetic deamidated gliadin peptides and tissue transglutaminase for the identification of childhood celiac disease

D Agardh - Clinical Gastroenterology and Hepatology, 2007 - Elsevier
Background & Aims: Children with celiac disease have antibodies against gliadin, tissue
transglutaminase (tTG), or both antigens. The aim was to evaluate immunoglobulin (Ig) A …

The prevalence of unrecognized adult celiac disease in Central Anatolia

S Gursoy, K Guven, T Simsek, A Yurci… - Journal of Clinical …, 2005 - journals.lww.com
Background: The aim of this study is to assess the prevalence of unrecognized adult celiac
disease in Central Anatolia of Turkey and establish if prevalence figures are similar to other …

Evaluation of the INOVA diagnostics enzyme-linked immunosorbent assay kits for measuring serum immunoglobulin G (IgG) and IgA to deamidated gliadin peptides

HE Prince - Clinical and Vaccine Immunology, 2006 - Am Soc Microbiol
New assays for antibodies to deamidated gliadin peptides (DGP) expressing celiac disease-
specific epitopes were evaluated using 154 sera previously tested for endomysial …

Serologic indicators of celiac disease

TM Rossi, A Tjota - Journal of pediatric gastroenterology and …, 1998 - journals.lww.com
Few controversies in the discipline of pediatric gastroenterology are viewed with less
emotion than the selection of the best serologic screening test for celiac disease. The current …

High prevalence of asymptomatic coeliac disease in Norway: a study of blood donors

N Hovdenak, E Hovlid, L Aksnes, G Fluge… - European journal of …, 1999 - journals.lww.com
Objective The prevalence of symptomatic coeliac disease in Norway is 1: 675. Coeliac
disease has previously been reported in presumably healthy people. Our airn was to …

Serum and Intestinal Celiac Disease–associated Antibodies in Children With Celiac Disease Younger Than 2 Years of Age

M Maglio, A Tosco, F Paparo, R Auricchio… - Journal of pediatric …, 2010 - journals.lww.com
Objectives: In children younger than 2 years of age, a diagnosis of celiac disease (CD) is
difficult to make because anti-endomysium (anti-EMA)/anti-tissue transglutaminase 2 (anti …