Sleep spindles are burstlike signals in the electroencephalogram (EEG) of the sleeping
mammalian brain and electrical surface correlates of neuronal oscillations in thalamus. As …

Neuromorphic computing covers a diverse range of approaches to information processing
all of which demonstrate some degree of neurobiological inspiration that differentiates them …

Hardware implementations of spiking neurons can be extremely useful for a large variety of
applications, ranging from high-speed modeling of large-scale neural systems to real-time …

Synapses are essential elements for computation and information storage in both real and
artificial neural systems. An artificial synapse needs to remember its past dynamical history …

The mechanisms through which general anaesthetics, an extremely diverse group of drugs,
cause reversible loss of consciousness have been a long-standing mystery. Gradually, a …

The human connectome will provide a detailed mapping of the brain's connectivity, with
fundamental insights for health and disease. However, further understanding of brain …

Consciousness is subjective experience. During both sleep and anesthesia consciousness
is common, evidenced by dreaming. A defining feature of dreaming is that, while conscious …

During non-rapid eye movement (NREM) sleep, synchronous synaptic activity in the
thalamocortical network generates predominantly low-frequency oscillations (< 4 Hz) that …

The thalamus is classically viewed as passively relaying information to the cortex. However,
there is growing evidence that the thalamus actively regulates information transmission to …

Dynamical modeling of neural systems and brain functions has a history of success over the
last half century. This includes, for example, the explanation and prediction of some features …